Fu H Q
Zhong Xi Yi Jie He Za Zhi. 1989 Mar;9(3):148-9, 132.
After giving Quingre-Lidan Prescription to the patients with biliary diseases, the authors observed the changes of bacteria in their bile employing anaerobic and aerobic culture techniques. The results suggested that among the bile specimens from 38 patients (hepatolithiasis in 32 and biliary duct tumour in 6), the anaerobes were detected in 68.4%, aerobes in 84.2%. The mean number of the isolated bacteria from those specimens was 3.3 species. Having taken the prescription for 3-14 days (mean 6.5 days), 33 cases among them received an operation for biliary diseases (hepatolithiasis in 32, biliary duct tumour in 1). The positive rate of anaerobes and aerobes in the bile was 42.4%, 97.0% respectively. The mean of bacteria was 2.5 species. The statistical analysis showed that the positive rate of anaerobic bacteria and the mean of bacteria all had significance before and after patients taking the prescription. The above observation explored the mechanism of Qingre-Lidan Prescription used for biliary infections in microbiology.