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钆对比剂的替代物:我们做到了吗?

Alternatives to GBCA: Are We There Yet?

作者信息

Wesolowski Jeffrey R, Kaiser Andrew

机构信息

University of Michigan Health System, Ann Arbor, MI.

出版信息

Top Magn Reson Imaging. 2016 Aug;25(4):171-5. doi: 10.1097/RMR.0000000000000096.

Abstract

Gadolinium has been widely used as the contrast agent of choice for magnetic resonance imaging (MRI). However, gadolinium administration is not always desired due to its inherent enhancement properties and potential side effects (nephrogenic systemic fibrosis). This article reviews gadolinium alternatives, iron-, and manganese- based agents, and their current clinical usage for contrast-enhanced MRI examinations.

摘要

钆已被广泛用作磁共振成像(MRI)的首选造影剂。然而,由于其固有的增强特性和潜在的副作用(肾源性系统性纤维化),钆的使用并非总是必要的。本文综述了钆的替代物、基于铁和锰的造影剂及其在对比增强MRI检查中的当前临床应用。

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