肥胖儿童视神经参数的频域光学相干断层扫描测量
Optic Nerve Parameters in Obese Children as Measured by Spectral Domain Optical Coherence Tomography.
作者信息
Koca Semra, Keskin Melikşah, Saricaoglu M Sinan, Koca Serkan Bilge, Duru Necati, Şahin Hamurcu Mualla, Şahin Muratoğlu Nursel, Aycan Zehra
机构信息
a Ankara Numune Training and Research Hospital , Ankara , Turkey.
b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey.
出版信息
Semin Ophthalmol. 2017;32(6):743-747. doi: 10.1080/08820538.2016.1177095. Epub 2016 Jul 1.
PURPOSE
To investigate whether an association exists between obesity and optic nerve parameters.
METHODS
This was a prospective comparative study including 125 eyes of 63 obese and 122 eyes of 62 healthy pediatric subjects. Optic nerve measurements were performed using the Cirrus spectral domain optical coherence tomograph (SD-OCT).
RESULTS
The disc area, cup volume, mean and vertical C/D ratio, inferior and temporal RNFL thickness values were significantly higher in the control group than the obese group; however, age, sex, mean, superior and nasal RNFL thickness and rim area measurements were not statistically significantly different between the two groups. Age was significantly negatively correlated with temporal RNFL thickness in the obese group. Girls had significantly higher rim area, mean and superior RNFL thickness, and lower cup volume and vertical C/D ratio than boys in the obese group.
CONCLUSION
These results could be helpful in the diagnosis and follow-up of obese children.
目的
研究肥胖与视神经参数之间是否存在关联。
方法
这是一项前瞻性对照研究，纳入了63名肥胖儿童的125只眼和62名健康儿童的122只眼。使用Cirrus频域光学相干断层扫描（SD-OCT）对视神经进行测量。
结果
对照组的视盘面积、杯容积、平均及垂直杯盘比、下方及颞侧视网膜神经纤维层（RNFL）厚度值均显著高于肥胖组；然而，两组间的年龄、性别、平均、上方及鼻侧RNFL厚度和边缘面积测量值无统计学显著差异。肥胖组中年龄与颞侧RNFL厚度显著负相关。肥胖组中女孩的边缘面积、平均及上方RNFL厚度显著高于男孩，杯容积和垂直杯盘比则低于男孩。
结论
这些结果可能有助于肥胖儿童的诊断和随访。
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