Cancer Discov. 2016 Aug;6(8):OF2. doi: 10.1158/2159-8290.CD-NB2016-086. Epub 2016 Jul 1.
A phase I study indicates that the combination of utomilumab, an investigational antibody that binds CD137, plus pembrolizumab is safe and well tolerated, yielding sustained responses in patients with various solid cancers.
一项 I 期研究表明,联合应用 utomilumab(一种靶向 CD137 的研究性抗体)加 pembrolizumab 是安全且耐受良好的,在多种实体瘤患者中产生了持续的反应。