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134例中枢神经系统白血病的临床分析

[Clinical analysis of 134 cases of central nervous system leukemia].

作者信息

Song Y X, Hou Y H

出版信息

Zhonghua Nei Ke Za Zhi. 1989 Feb;28(2):99-102, 127.

PMID:2737044
Abstract

134 cases of central nervous system leukemia (CNSL) were reported. The clinical manifestations and the relationship of its occurrence with the duration of the disease and the effectiveness of prophylaxis were discussed. It was found that most cases of CNSL occurred 3 months after the diagnosis of leukemia. It was quite different from the reports in literature that most CNSL usually occurred after complete remission, with CSF routine examination the into cranial pressure, the protein content, the white cell count and the smear for leukemic cells were of significant diagnostic help. Among these, the founding of leukemic cells in the fresh specimen by using natural precipitation method is the most reliable diagnostic criterion of CNSL.

摘要

报告了134例中枢神经系统白血病(CNSL)。讨论了其临床表现、发病与病程的关系以及预防效果。发现大多数CNSL病例在白血病诊断后3个月发生。这与文献报道有很大不同,文献报道大多数CNSL通常在完全缓解后发生,脑脊液常规检查中颅内压、蛋白质含量、白细胞计数及白血病细胞涂片对诊断有重要帮助。其中,采用自然沉淀法在新鲜标本中发现白血病细胞是CNSL最可靠的诊断标准。

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