Usui Yuko, Kakuta Risako, Araki Makoto, Sato Taigo, Gu Yoshiaki, Yano Hisakazu, Taniuchi Norihide
Department of Internal Medicine, Suwa Central Hospital, Japan.
Intern Med. 2016;55(13):1811-3. doi: 10.2169/internalmedicine.55.6080. Epub 2016 Jul 1.
In Japan, routine Haemophilus influenzae type b (Hib) vaccination began in 2013. Thus, similar to other countries, a strain shift is expected in the near future. We experienced a case of H. influenzae type f (Hif) bacteremia in a 66-year-old man. The primary focus of the infection was the soft tissue of the left lower leg, which is an extremely rare origin in adults. Subsequently, we conducted multilocus sequence typing and identified the strain as sequence type 124, which is the most common invasive strain of Hif worldwide. This case may mark the beginning of an Hif strain shift in Japan.
在日本，b型流感嗜血杆菌（Hib）常规疫苗接种于2013年开始。因此，与其他国家类似，预计在不久的将来会出现菌株转变。我们遇到了一例66岁男性的f型流感嗜血杆菌（Hif）菌血症病例。感染的主要病灶是左小腿的软组织，这在成人中是极为罕见的感染源。随后，我们进行了多位点序列分型，并将该菌株鉴定为序列型124，这是全球范围内Hif最常见的侵袭性菌株。该病例可能标志着日本Hif菌株转变的开始。
