Kloc Grzegorz, Budziak Małgorzata, Więckiewicz Agnieszka, Pleśniak Mateusz, Bartosik-Psujek Halina
Clinical Department of Neurology, Rzeszow State Hospital No 2, Rzeszow, Poland.
Clinical Department of Neurology, Rzeszow State Hospital No 2, Rzeszow, Poland.
Neurol Neurochir Pol. 2016 Jul-Aug;50(4):313-7. doi: 10.1016/j.pjnns.2016.04.007. Epub 2016 Apr 26.
Diagnosis of relapsing-remitting multiple sclerosis requires demonstration disseminated symptoms in time and space on the basis of neurological assessment or magnetic resonance imaging findings. In addition, the diagnosis is conditioned by ruling out other conditions that may explain the clinical symptoms. We describe the patient presenting in the initial stage of the disease neurological symptoms and magnetic resonance imaging lesions, that met criteria for relapsing-remitting multiple sclerosis diagnosis. The patient was administered immunomodulatory treatment. However, the subsequent course of the disease tended to verify the diagnosis. Finally, the patient was diagnosed with intravascular B-cell lymphoma. Intravascular lymphoma is a rare form of lymphoma characterized by the development of cancerous cells in the lumen of small and medium-sized blood vessels. Due to the lack of characteristic biomarkers in laboratory tests and neuroimaging, the diagnosis is based on histopathological examination of the sample of the affected organ taken by biopsy. It should be consider in all cases of central nervous system damage of unknown, undiagnosed etiology.
复发缓解型多发性硬化症的诊断需要根据神经学评估或磁共振成像结果，证明在时间和空间上存在弥散性症状。此外，诊断的前提是排除其他可能解释临床症状的疾病。我们描述了一名在疾病初期出现神经症状和磁共振成像病变的患者，该患者符合复发缓解型多发性硬化症的诊断标准。对该患者进行了免疫调节治疗。然而，疾病的后续病程倾向于证实诊断结果。最终，该患者被诊断为血管内B细胞淋巴瘤。血管内淋巴瘤是一种罕见的淋巴瘤形式，其特征是在中小血管腔内出现癌细胞。由于实验室检查和神经影像学缺乏特征性生物标志物，诊断基于通过活检获取的受影响器官样本的组织病理学检查。对于所有病因不明、未确诊的中枢神经系统损伤病例，均应考虑该病。
