Hammer F, Schreiner W E
Gynakol Rundsch. 1989;29(2):78-92.
Between 1971 and 1980, 177 patients were treated for a carcinoma of the uterine cervix (145 stage Ib, 32 stage IIa) in the Department of Gynecology and Obstetrics at the University Hospital Zürich, Switzerland. There were 115 patients who underwent radical hysterectomy combined with pelvic lymphadenectomy. Of these, 91 also received radiotherapy. Surgery could not be performed on 62 patients due to internal medical problems and risks presented by anaesthesia. They were treated solely by combined radiotherapy. Of the 177 patients, 79.5% had a squamous-cell carcinoma, 14.8% an adenocarcinoma and the other 5.7% rare types of carcinomas. Of the 115 patients who were operated, metastases of pelvic lymph nodes were found in 13% and an infiltrative carcinoma of the parametrium in 8.7%. The most severe complications we had were uretero- or vesicovaginal fistulas (5.2% of all operated patients). No significant statistical difference was found in the results of the three methods of treatment. The 5-year survival rate in stage Ib was between 61 and 81% (non corrected) and between 75 and 85% (corrected). In stage IIa, there were not enough patients for valid statistical conclusions to be drawn.
1971年至1980年间，瑞士苏黎世大学医院妇产科收治了177例子宫颈癌患者（145例Ib期，32例IIa期）。其中115例患者接受了根治性子宫切除术加盆腔淋巴结清扫术。这些患者中，91例还接受了放射治疗。由于内科疾病和麻醉风险，62例患者无法进行手术，仅接受了联合放射治疗。177例患者中，79.5%为鳞状细胞癌，14.8%为腺癌，其余5.7%为罕见类型的癌。在接受手术的115例患者中，盆腔淋巴结转移率为13%，宫旁浸润癌发生率为8.7%。最严重的并发症是输尿管或膀胱阴道瘘（占所有手术患者的5.2%）。三种治疗方法的结果未发现显著统计学差异。Ib期的5年生存率在61%至81%（未校正）之间，在75%至85%（校正）之间。IIa期患者数量不足，无法得出有效的统计学结论。
