缺铁性贫血患者对口服铁剂治疗的用药依从性。
Medication adherence to oral iron therapy in patients with iron deficiency anemia.
作者信息
Gereklioglu Cigdem, Asma Suheyl, Korur Asli, Erdogan Ferit, Kut Altug
机构信息
Cigdem Gereklioglu, MD. Department of Family Medicine, Baskent University Medical School, Adana, Turkey.
Suheyl Asma, Assistant Professor, Department of Family Medicine, Baskent University Medical School, Adana, Turkey.
出版信息
Pak J Med Sci. 2016 May-Jun;32(3):604-7. doi: 10.12669/pjms.323.9799.
Abstract
OBJECTIVE
This study aimed at investigating the factors affecting medication adherence in patients who use oral iron therapy due to iron deficiency anemia.
METHODS
A total of 96 female patients in fertile age with mean age of 30±10.1 years (range 18-53) who were admitted to Family Medicine Clinic between 01 January and 31 March 2015 and who had received iron therapy within the recent three years were enrolled in the study. Data were collected through a questionnaire form.
RESULTS
Of the patients, 39 (40,6%) were detected not to use the medication regularly or during the recommended period. A statistically significant relationship was found between non-adherence to therapy and gastrointestinal side effects and weight gain (p<0.05).
CONCLUSION
Medication adherence is deficient in patients with iron deficiency anemia. The most important reason for this seems gastrointestinal side effects, in addition to weight gain under treatment.
摘要
目的
本研究旨在调查缺铁性贫血患者口服铁剂治疗时影响用药依从性的因素。
方法
选取2015年1月1日至3月31日期间入住家庭医学诊所、年龄在18 - 53岁之间、平均年龄为30±10.1岁的96名育龄期女性患者，她们在最近三年内接受过铁剂治疗。通过问卷调查收集数据。
结果
在这些患者中，39名（40.6%）被发现未按常规或在推荐疗程内用药。未坚持治疗与胃肠道副作用及体重增加之间存在统计学显著相关性（p<0.05）。
结论
缺铁性贫血患者的用药依从性较差。除治疗期间体重增加外，最重要的原因似乎是胃肠道副作用。
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