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缺铁性贫血患者口服铁剂补充指南依从性评估:一项横断面研究。

Assessment of Adherence to Oral Iron Supplementation Guidelines in Patients With Iron Deficiency Anemia: A Cross-Sectional Study.

作者信息

Ambreen Ambreen, Habib Aleeza, Hassan Sajjad Ali, Jawad Malik Ali, Javed Qasim

机构信息

Internal Medicine, Shifa International Hospital Faisalabad, Faisalabad, PAK.

Internal Medicine, Gujranwala Medical College, Gujranwala, PAK.

出版信息

Cureus. 2025 Jul 10;17(7):e87681. doi: 10.7759/cureus.87681. eCollection 2025 Jul.

Abstract

Background and objective The most common kind of anemia in the world is iron deficiency anemia (IDA), and following recommendations for oral iron supplements is still crucial to the effectiveness of therapy. The main objective of this study is to assess the level of adherence to oral iron supplementation guidelines among patients with IDA, focusing on prescribing practices, patient compliance, and follow-up monitoring in a clinical setting. Methodology A two-phase cross-sectional clinical audit was conducted in the Outpatient Medical Departments of Gujranwala Medical College and Allied Teaching Hospitals, Gujranwala, Pakistan. Convenience sampling was used to recruit 278 adult individuals with an IDA diagnosis who were provided oral iron treatment. From January to June 2023, Phase 1 (n = 139) was carried out. This was followed by an intervention phase that included patient information leaflets and physician education. The second phase (n = 139) took place between October 2023 and March 2024. A 10-point audit proforma was used to evaluate adherence, with scores classified as excellent (≥8), moderate (5-7), or poor (≤4). IBM SPSS Statistics for Windows, Version 25 (released 2017; IBM Corp., Armonk, NY, USA) was used to analyze the data, and a paired-sample t-test was used to assess statistical significance. Results Good adherence was shown by 41 out of 139 patients (29.50%) in Phase 1 and 79 out of 139 patients (56.83%) in Phase 2. The number of patients with poor adherence dropped from 34 (24.46%) to 16 (11.51%). There was a substantial improvement in the mean adherence score, from 5.43 ± 1.78 to 7.26 ± 1.45 (p < 0.001). In Phase 2, 131 patients (94.24%) received written teaching materials, but in Phase 1, none were provided. Follow-up monitoring, including hemoglobin/ferritin reassessment, rose from 63 patients (45.32%) to 117 patients (84.17%). Conclusions Targeted educational interventions significantly improved adherence to oral iron supplementation guidelines among patients with IDA.

摘要

背景与目的 缺铁性贫血(IDA)是世界上最常见的贫血类型,遵循口服铁剂补充建议对于治疗效果仍然至关重要。本研究的主要目的是评估IDA患者对口服铁剂补充指南的依从程度,重点关注临床环境中的处方实践、患者依从性和随访监测。方法 在巴基斯坦古杰兰瓦拉医学院及其附属教学医院的门诊进行了两阶段横断面临床审计。采用便利抽样法招募了278名诊断为IDA且接受口服铁剂治疗的成年个体。2023年1月至6月进行了第一阶段(n = 139)。随后是一个干预阶段,包括患者信息传单和医生教育。第二阶段(n = 139)于2023年10月至2024年3月进行。使用10分制审计表格评估依从性,分数分为优秀(≥8分)、中等(5 - 7分)或差(≤4分)。使用IBM SPSS Statistics for Windows,版本25(2017年发布;IBM公司,美国纽约州阿蒙克)分析数据,并使用配对样本t检验评估统计学意义。结果 第一阶段139名患者中有41名(29.50%)表现出良好依从性,第二阶段139名患者中有79名(56.83%)表现出良好依从性。依从性差的患者数量从34名(24.46%)降至16名(11.51%)。平均依从性得分有显著提高,从5.43 ± 1.78提高到7.26 ± 1.45(p < 0.001)。在第二阶段,131名患者(94.24%)收到了书面教材,但在第一阶段,没有患者收到。包括血红蛋白/铁蛋白重新评估在内的随访监测从63名患者(45.32%)增加到117名患者(84.17%)。结论 有针对性的教育干预显著提高了IDA患者对口服铁剂补充指南的依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4db/12335328/de8d983294f7/cureus-0017-00000087681-i01.jpg

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