Freeman Nadia, Quigley Paul
Emergency Medicine, Capital & Coast District Health Board, Private Bag 7902, Wellington, New Zealand.
N Z Med J. 2015 Oct 30;128(1424):28-34.
To examine statistics on paracetamol overdose in New Zealand and investigate options to reduce paracetamol overdose rates, through supply reduction strategies.
Data was gathered from the Ministry of Health's National Minimum Dataset and Wellington Hospital Emergency Department attendances. Twenty articles on supply reduction strategies were sourced through article database searches. A survey on paracetamol availability from online pharmacies within New Zealand was conducted by searching for New Zealand online pharmacies through Google.
A five-year audit of data (2007-2012) from the Wellington Hospital Emergency Department revealed that paracetamol was the most common medication used for overdose (23%). National data on aminophenol derivatives accounted for 22.4% of poisonings in New Zealand's public hospitals. An online search found that 25 out of 27 online pharmacies sold packets containing 50 grams of paracetamol. However, the literature supported restricting packets to the minimum threshold for an acute exposure (10 g).
Paracetamol poisoning is the most common form of drug overdose in many developed countries. Tightening restrictions on the quantity of paracetamol sold per packet, in all outlets in New Zealand, may be an effective strategy to reduce overdose rates. This includes online pharmacies where large quantities of paracetamol per packet are available for sale.
研究新西兰对乙酰氨基酚过量服用的统计数据，并通过减少供应策略探讨降低对乙酰氨基酚过量服用率的方法。
数据收集自卫生部的国家最低数据集以及惠灵顿医院急诊科的就诊情况。通过文章数据库搜索获取了20篇关于减少供应策略的文章。通过谷歌搜索新西兰在线药房，对新西兰在线药房的对乙酰氨基酚供应情况进行了一项调查。
对惠灵顿医院急诊科五年（2007 - 2012年）的数据审核显示，对乙酰氨基酚是过量服用时最常用的药物（23%）。新西兰公立医院中氨基酚衍生物的全国数据占中毒病例的22.4%。在线搜索发现，27家在线药房中有25家出售含50克对乙酰氨基酚的包装。然而，文献支持将包装限制在急性暴露的最低阈值（10克）。
在许多发达国家，对乙酰氨基酚中毒是药物过量服用的最常见形式。在新西兰的所有销售点，收紧每包对乙酰氨基酚的销售数量限制，可能是降低过量服用率的有效策略。这包括那些有大量每包对乙酰氨基酚出售的在线药房。
