Trewatcharegon S, Apibal S, Bunyaratvej A, Fucharoen S
J Med Assoc Thai. 1989 Feb;72(2):67-70.
The mean +/- S.D. of LAP score in neutrophil of the normal control, non splenectomised patients and splenectomised patients were 116 +/- 78, 94 +/- 48 and 37 +/- 23 Kaplow units, respectively. The significant reduction in the leukocyte alkaline phosphatase level (P less than 0.05) was found in beta thalassemia/HbE patients. The degree of reduction was greater in the splenectomised patients (P less than 0.05). The decreased LAP levels in PMN was persistent. This was in contrast to the LAP in PMN of other patients where as LAP returned to normal after splenectomy. The relevance to the increased susceptibility to infection and low LAP in beta thalassemia/HbE should be further investigated.
正常对照组、未行脾切除术患者和行脾切除术患者中性粒细胞中LAP评分的平均值±标准差分别为116±78、94±48和37±23卡普洛单位。在β地中海贫血/HbE患者中发现白细胞碱性磷酸酶水平显著降低（P<0.05）。行脾切除术患者的降低程度更大（P<0.05）。PMN中LAP水平的降低是持续的。这与其他患者PMN中的LAP不同，其他患者脾切除术后LAP恢复正常。β地中海贫血/HbE患者对感染易感性增加和LAP降低的相关性应进一步研究。
