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犬猫炎症性疾病贫血综述。

A review of anaemia of inflammatory disease in dogs and cats.

作者信息

Chikazawa S, Dunning M D

机构信息

Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23-35-1 Towada, Aomori 034-8628, Japan.

Department of Medicine and Health Sciences, School of Veterinary Medicine, University of Nottingham, Sutton Bonington Campus, Leicestershire, LE12 5RD.

出版信息

J Small Anim Pract. 2016 Jul;57(7):348-53. doi: 10.1111/jsap.12498.

Abstract

Anaemia of inflammatory disease is a common cause of anaemia in routine veterinary practice. It is most often mild to moderate, normocytic, normochromic and non-regenerative. Shortened red cell life span, inhibition of iron metabolism and impaired bone marrow response to erythropoietin all contribute to its development. Although anaemia of inflammatory disease is a well-known cause of anaemia in dogs and cats, there is a lack of epidemiological information because specific diagnostic criteria have not been established in veterinary species. Anaemia of inflammatory disease is associated with a poor outcome in various disease states in human medicine; however, its clinical significance and treatment in veterinary medicine are not well understood. This review article describes anaemia of inflammatory disease in dogs and cats and considers its potential significance.

摘要

炎症性疾病贫血是常规兽医实践中贫血的常见原因。它通常为轻度至中度,正细胞、正色性且非再生性。红细胞寿命缩短、铁代谢抑制以及骨髓对促红细胞生成素的反应受损均促成其发展。尽管炎症性疾病贫血是犬猫贫血的一个众所周知的原因,但由于尚未在兽医物种中确立特定的诊断标准,所以缺乏流行病学信息。在人类医学中,炎症性疾病贫血与各种疾病状态下的不良预后相关;然而,其在兽医学中的临床意义和治疗方法尚未得到充分了解。这篇综述文章描述了犬猫的炎症性疾病贫血,并探讨了其潜在意义。

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