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[残胃癌复发致脾脏转移1例罕见病例]

[A rare case of metastasis of the spleen from recurrent cancer of the residual stomach].

作者信息

Fujita M, Yamazaki S, Morioka G, Machida J, Ochiai K, Ozawa M, Ohtsuki H, Shimoyama N, Ishidate T

机构信息

Dept. of Surgery, Hakodate Municipal Hospital.

出版信息

Gan No Rinsho. 1989 Jun;35(7):855-60.

PMID:2739077
Abstract

In May, 1988, a 75-year-old housewife, who had undergone a subtotal gastrectomy for a carcinoma 12 years earlier, visited our hospital because of vomiting. Biopsy specimens of the residual gastric mucosa revealed malignant cells and an abdominal CT scanning examination showed a solitary nodule in the splenic parenchyma. A non-curative resection of the residual stomach, a splenectomy and a distal pancreatectomy were performed on June 3, 1988. Histological examination of the resected specimens demonstrated a moderately differentiated adenocarcinoma of the stomach, that had invaded the pancreas and retroperitoneal nodes. A nodule of the spleen that was inspected showed a round, greyish solid mass, 0.7 cm in diameter on the cut surface, and microscopically metastatic focus from a gastric cancer. Only a few operated cases manifesting a splenic metastasis of a gastric cancer have been reported and a definitive routing pattern of the metastasis is often difficult to distinguish. However, our case seems to suggest that a hemodynamic route had been taken, since there were no metastatic nodes around the splenic hilus and the metastatic site was only the parenchyma in the spleen.

摘要

1988年5月,一位75岁的家庭主妇因呕吐前来我院就诊。12年前她曾因患癌接受过胃次全切除术。残余胃黏膜活检标本发现了恶性细胞,腹部CT扫描检查显示脾实质内有一个孤立结节。1988年6月3日,对残余胃进行了非根治性切除、脾切除术和远端胰腺切除术。切除标本的组织学检查显示为胃中分化腺癌,已侵犯胰腺和腹膜后淋巴结。检查的脾脏结节在切面上显示为一个直径0.7厘米的圆形、灰白色实性肿块,显微镜下为胃癌转移灶。仅有少数胃癌脾转移的手术病例被报道,转移的确切途径模式往往难以区分。然而,我们的病例似乎提示采取了血流动力学途径,因为脾门周围没有转移淋巴结,转移部位仅在脾实质。

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