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中枢神经肽是否与颈动脉窦反射过敏有关?

Can central neuropeptides be implicated in carotid sinus reflex hypersensitivity?

作者信息

Baig M W, Kaye G C, Perrins E J

机构信息

Department of Medical Cardiology, General Infirmary, Leeds, England, U.K.

出版信息

Med Hypotheses. 1989 Apr;28(4):255-9. doi: 10.1016/0306-9877(89)90079-0.

DOI:10.1016/0306-9877(89)90079-0
PMID:2739593
Abstract

Carotid sinus reflex hypersensitivity involves profound and intermittent changes in heart rate and blood pressure associated with symptoms of dizziness and syncope. This involves a reflex arc in which the main defect is believed to lie within the central nervous system. The discovery of classical and peptidergic neurotransmitters within the same neurone, and the presence of these peptides within the central nervous system raises the possibility that carotid sinus reflex hypersensitivity may be related to an abnormality of peptide distribution or function.

摘要

颈动脉窦反射过敏涉及心率和血压的显著且间歇性变化,并伴有头晕和晕厥症状。这涉及一个反射弧,其主要缺陷被认为存在于中枢神经系统内。在同一神经元内发现经典神经递质和肽能神经递质,以及这些肽在中枢神经系统中的存在,增加了颈动脉窦反射过敏可能与肽分布或功能异常有关的可能性。

相似文献

1
Can central neuropeptides be implicated in carotid sinus reflex hypersensitivity?中枢神经肽是否与颈动脉窦反射过敏有关?
Med Hypotheses. 1989 Apr;28(4):255-9. doi: 10.1016/0306-9877(89)90079-0.
2
Carotid sinus hypersensitivity and the carotid sinus syndrome.颈动脉窦过敏症与颈动脉窦综合征
Prog Cardiovasc Dis. 1989 Mar-Apr;31(5):379-91. doi: 10.1016/0033-0620(89)90032-7.
3
Alterations in reflex function contributing to syncope: orthostatic hypotension, carotid sinus hypersensitivity and drug-induced dysfunction.导致晕厥的反射功能改变:直立性低血压、颈动脉窦过敏及药物诱发的功能障碍。
Herz. 1993 Jun;18(3):164-74.
4
[Carotid sinus hypersensitivity syndrome--diagnostic and clinical problem].[颈动脉窦过敏综合征——诊断与临床问题]
Wiad Lek. 1992 Aug;45(15-16):606-9.
5
Sympathoinhibition and hypotension in carotid sinus hypersensitivity.
Clin Auton Res. 1992 Dec;2(6):389-92. doi: 10.1007/BF01831396.
6
Pure vasodepressor carotid sinus hypersensitivity. Unusual cause of recurrent syncope.
Am J Med. 1986 Dec;81(6):1095-7. doi: 10.1016/0002-9343(86)90417-1.
7
Carotid sinus syndrome--clinical characteristics in elderly patients.颈动脉窦综合征——老年患者的临床特征
Age Ageing. 1991 Nov;20(6):449-54. doi: 10.1093/ageing/20.6.449.
8
At the heart of the arterial baroreflex: a physiological basis for a new classification of carotid sinus hypersensitivity.动脉压力感受反射的核心:颈动脉窦敏感性的一种新分类的生理学基础。
J Intern Med. 2013 Apr;273(4):345-58. doi: 10.1111/joim.12042.
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Enhanced vagal activity and normal arginine vasopressin response in carotid sinus syndrome: implications for a central abnormality in carotid sinus hypersensitivity.颈动脉窦综合征中迷走神经活动增强及精氨酸加压素反应正常:对颈动脉窦过敏中枢异常的影响
Cardiovasc Res. 1987 Jul;21(7):545-50. doi: 10.1093/cvr/21.7.545.
10
Observations on carotid sinus hypersensitivity from direct intraneural recordings of sympathetic nerve traffic.通过交感神经活动的直接神经内记录对颈动脉窦过敏的观察。
Am J Cardiol. 1996 Jun 15;77(15):1362-5. doi: 10.1016/s0002-9149(96)00207-x.

引用本文的文献

1
Should We Ever Pace for Carotid Sinus Syndrome?我们应该对颈动脉窦综合征进行起搏治疗吗?
Front Cardiovasc Med. 2020 Apr 22;7:44. doi: 10.3389/fcvm.2020.00044. eCollection 2020.
2
Exaggerated carotid sinus massage responses are related to severe coronary artery disease in patients being evaluated for chest pain.在因胸痛接受评估的患者中,颈动脉窦按摩反应过度与严重冠状动脉疾病有关。
Clin Cardiol. 2002 Apr;25(4):161-6. doi: 10.1002/clc.4960250406.