Sainio K, Rautonen J, Siimes M A
Children's Hospital, University of Helsinki, Finland.
Neuropediatrics. 1989 May;20(2):82-3. doi: 10.1055/s-2008-1071270.
The EEG was recorded in 110 patients with acute lymphoblastic leukemia at the time of diagnosis, in 25 at the time of relapse and in 62 patients at discontinuation of treatment. At the time of diagnosis the EEG was abnormal in 60% of the patients. The abnormality showed no correlation with the prognosis. The EEG was correlated with the leukocytosis of the CSF and with the immunologic cell type of the leukemia. At the time of relapse the EEGs did not differ from those obtained at the time of diagnosis. No specific features distinguished the EEGs of the patients with CNS relapse. At discontinuation of treatment the EEG was abnormal in 31% of the patients. The EEG was not correlated with the method of CNS prophylaxis. Thus, it seems that the usefulness of electroencephalography in leukemic patients lies mainly in the diagnosis of neurologic complications.
对110例急性淋巴细胞白血病患者在诊断时进行了脑电图记录，25例在复发时进行了记录，62例在治疗中断时进行了记录。诊断时，60%的患者脑电图异常。这种异常与预后无关。脑电图与脑脊液白细胞增多以及白血病的免疫细胞类型相关。复发时的脑电图与诊断时获得的脑电图没有差异。没有特定特征可区分中枢神经系统复发患者的脑电图。治疗中断时，31%的患者脑电图异常。脑电图与中枢神经系统预防方法无关。因此，脑电图在白血病患者中的作用似乎主要在于诊断神经并发症。
