Gurd J M, Ward C D
Department of Experimental Psychology, University of Oxford, U.K.
Neuropsychologia. 1989;27(5):743-6. doi: 10.1016/0028-3932(89)90120-6.
We report the impaired performance by a group of 27 patients with Parkinson's disease (vs matched controls) on semantic and letter-initial verbal fluency tasks, carried out in both single and alternating category conditions. Individual differences in fluency were significantly correlated with confrontation picture naming scores in the patient group, but not in control subjects. However, the PD patients showed no significant correlation between verbal fluency scores, and rate of reciting days of the week as rapidly as possible. Both controls and patients produced more items when retrieving words from a single category than when alternately retrieving words from two categories. The magnitude of the decrement was nonetheless no greater in the patient than in the control population. This finding shows that "task switching" per se is not impaired in PD. We suggest that the verbal fluency deficit, while it may in part be attributed to motor-speech factors, primarily reflects an underlying cognitive disorder.
我们报告了一组27名帕金森病患者（与匹配的对照组相比）在语义和首字母言语流畅性任务中的表现受损情况，这些任务在单一类别和交替类别条件下进行。患者组中流畅性的个体差异与对图片命名的得分显著相关，但对照组中并非如此。然而，帕金森病患者的言语流畅性得分与尽可能快速背诵一周日期的速度之间没有显著相关性。对照组和患者在从单一类别中检索单词时比从两个类别中交替检索单词时产生的项目更多。然而，患者组中下降的幅度并不比对照组更大。这一发现表明帕金森病患者本身的“任务转换”能力并未受损。我们认为言语流畅性缺陷虽然部分可能归因于运动言语因素，但主要反映了一种潜在的认知障碍。
