De Vitis Luigi Antonio, Benatti Lucia, Tomasso Livia, Baldin Giovanni, Carnevali Adriano, Querques Lea, Querques Giuseppe, Bandello Francesco
Department of Ophthalmology, Vita-Salute San Raffaele University, IRCCS Ospedale San Raffaele, Milan, Italy.
Ophthalmic Res. 2016;56(3):155-62. doi: 10.1159/000447094. Epub 2016 Jul 12.
To compare the performance of two different spectral-domain optical coherence tomography angiography (OCTA) devices in clinical practice by evaluating examination execution time and the number of motion artifacts per image.
Seventy-six patients affected by different ocular diseases and 13 healthy subjects consecutively underwent assessments by two different OCTA devices: AngioPlex (Zeiss Meditec, Inc., Dublin, Calif., USA) and AngioVue (OptoVue, Inc., Fremont, Calif., USA). Two different operators (L.A.D.V. and L.B.) measured execution times, excluded low-quality images, and counted the number of motion artifacts per image.
The mean execution time was shorter with AngioPlex than with AngioVue for all subjects (3 min 32 s ± 1 min 45 s vs. 4 min 35 s ± 1 min 11 s; p < 0.0001), for the healthy subjects (2 min 31 s ± 45 s vs. 4 min 1 s ± 53 s; p = 0.003), and for the patients (3 min 44 s ± 1 min 48 s vs. 4 min 42 s ± 1 min 13 s; p < 0.0001). The percentages of available images, low-signal-strength images, and images impossible to analyze of the total acquired images obtained using AngioPlex or AngioVue were 85, 6, and 9% and 56, 29, and 15%, respectively. The mean number of motion artifacts was significantly lower in images obtained using AngioPlex than in images obtained using AngioVue for all patients (6.5 ± 5.9 vs. 12.6 ± 8.5; p < 0.0001), for the healthy subjects (6.5 ± 4.6 vs. 10.9 ± 7.9; p = 0.0009), and for the patients (6.6 ± 6.3 vs. 13.1 ± 8.7; p < 0.0001). There was no correlation between the number of artifacts and execution time or patients' age.
AngioPlex and AngioVue are useful devices in clinical practice. AngioPlex requires a shorter execution time and provides a higher number of images available for analysis with fewer motion artifacts.
通过评估检查执行时间和每张图像中运动伪影的数量，比较两种不同的光谱域光学相干断层扫描血管造影（OCTA）设备在临床实践中的性能。
76例患有不同眼部疾病的患者和13名健康受试者连续接受了两种不同的OCTA设备的评估：AngioPlex（蔡司医疗技术公司，美国加利福尼亚州都柏林）和AngioVue（奥普托维公司，美国加利福尼亚州弗里蒙特）。两名不同的操作人员（L.A.D.V.和L.B.）测量执行时间，排除低质量图像，并计算每张图像中运动伪影的数量。
对于所有受试者，AngioPlex的平均执行时间比AngioVue短（3分32秒±1分45秒对4分35秒±1分11秒；p<0.0001），对于健康受试者（2分31秒±45秒对4分1秒±53秒；p=0.003），对于患者（3分44秒±1分48秒对4分42秒±1分13秒；p<0.0001）。使用AngioPlex或AngioVue获得的总采集图像中，可用图像、低信号强度图像和无法分析的图像的百分比分别为85%、6%和9%以及56%、29%和15%。对于所有患者（6.5±5.9对12.6±8.5；p<0.0001）、健康受试者（6.5±4.6对10.9±7.9；p=0.0009）和患者（6.6±6.3对13.1±8.7；p<0.0001），使用AngioPlex获得的图像中的运动伪影平均数量显著低于使用AngioVue获得的图像。伪影数量与执行时间或患者年龄之间无相关性。
AngioPlex和AngioVue在临床实践中都是有用的设备。AngioPlex需要更短的执行时间，并提供更多可用于分析的图像，且运动伪影更少。
