Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA.
Department of Pediatrics, Division of Rheumatology, Allergy, and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA.
Curr Allergy Asthma Rep. 2016 Jul;16(8):55. doi: 10.1007/s11882-016-0632-7.
Immune gamma globulin (IgG) has a long history in the treatment of both primary immune deficiency and autoimmune disorders. Disease indications continue to expand and new-generation products increase the versatility of delivery. This review encompasses a historical perspective as well as current and future implications of human immune globulin for the treatment of immune-mediated illness.
免疫球蛋白 G(IgG)在原发性免疫缺陷和自身免疫性疾病的治疗中有着悠久的历史。疾病适应证不断扩大,新一代产品增加了给药的多功能性。本文综述了人免疫球蛋白治疗免疫介导性疾病的历史背景,以及当前和未来的影响。