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儿童高血压左心室肥厚:寻求定义。

Left Ventricular Hypertrophy in Children with Hypertension: in Search of a Definition.

机构信息

Division of Pediatric Nephrology, Cohen Children's Medical Center of New York, 269-01 76th Avenue, 11040, New Hyde Park, NY, USA.

Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Curr Hypertens Rep. 2016 Aug;18(8):65. doi: 10.1007/s11906-016-0672-3.

DOI:10.1007/s11906-016-0672-3
PMID:27402014
Abstract

PURPOSE OF REVIEW

The purpose of this review is to provide background on the importance of left ventricular hypertrophy (LVH) in children with hypertension, to highlight various diagnostic modalities and measures for defining LVH, and to demonstrate the need for standardization and a consensus definition for LVH in the pediatric population.

RECENT FINDINGS

There is no clear consensus among specialists performing echocardiograms and treating clinicians on the definition of LVH in children with hypertension. In fact, there is considerable variation in every step of the evaluation of pediatric LVH. There is variation in every step of the assessment of LVH in the pediatric population. This variation exists in imaging modality, the type of measurement used, the method of calculating left ventricular mass (LVM), the method of indexing LVM to body size, the normalization method for the index used, the reference data used, the inclusion of confounders, the implementation in clinical practice, and the format for echocardiography reporting.

摘要

目的综述

本文旨在介绍左心室肥厚(LVH)在高血压儿童中的重要性,重点介绍用于定义 LVH 的各种诊断方式和测量方法,并论证在儿科人群中对 LVH 进行标准化和达成共识定义的必要性。

最近的发现

在进行超声心动图检查的专家和治疗临床医生中,对于高血压儿童中 LVH 的定义尚无明确共识。事实上,在评估儿科 LVH 的每一步都存在相当大的差异。在儿科人群中评估 LVH 的每一步都存在差异。这种差异存在于成像方式、使用的测量类型、计算左心室质量(LVM)的方法、将 LVM 索引到身体大小的方法、所使用的索引归一化方法、所使用的参考数据、混杂因素的纳入、在临床实践中的实施以及超声心动图报告的格式。

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本文引用的文献

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Impact and pitfalls of scaling of left ventricular and atrial structure in population-based studies.基于人群的研究中左心室和心房结构测量的影响与陷阱
J Hypertens. 2016 Jun;34(6):1186-94. doi: 10.1097/HJH.0000000000000922.
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The Prevalence of Left Ventricular Hypertrophy in Obese Children Varies Depending on the Method Utilized to Determine Left Ventricular Mass.肥胖儿童左心室肥厚的患病率因用于确定左心室质量的方法而异。
Pediatr Cardiol. 2016 Aug;37(6):993-1002. doi: 10.1007/s00246-016-1380-0. Epub 2016 Mar 31.
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Left ventricular hypertrophy and diastolic function in children and adolescents with essential hypertension.
4岁儿童出生体重与心血管参数之间关联的性别差异:一项中国队列研究。
Front Nutr. 2021 Oct 26;8:756512. doi: 10.3389/fnut.2021.756512. eCollection 2021.
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Reference Intervals and Percentile Curves of Echocardiographic Left Ventricular Mass, Relative Wall Thickness and Ejection Fraction in Healthy Children and Adolescents.健康儿童和青少年超声心动图左心室质量、相对室壁厚度和射血分数的参考区间及百分位数曲线
Pediatr Cardiol. 2019 Feb;40(2):283-301. doi: 10.1007/s00246-018-2000-y. Epub 2018 Oct 4.
原发性高血压儿童及青少年的左心室肥厚与舒张功能
Clin Hypertens. 2015 Oct 22;21:21. doi: 10.1186/s40885-015-0031-8. eCollection 2015.
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New Reference Centiles for Left Ventricular Mass Relative to Lean Body Mass in Children.儿童左心室质量相对于去脂体重的新参考百分位数。
J Am Soc Echocardiogr. 2016 May;29(5):441-447.e2. doi: 10.1016/j.echo.2015.12.011. Epub 2016 Feb 3.
5
Left Ventricular Mass Indexing in Infants, Children, and Adolescents: A Simplified Approach for the Identification of Left Ventricular Hypertrophy in Clinical Practice.婴幼儿及青少年的左心室质量指数:临床实践中用于识别左心室肥厚的简化方法。
J Pediatr. 2016 Mar;170:193-8. doi: 10.1016/j.jpeds.2015.10.085. Epub 2015 Dec 6.
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Left Ventricular Hypertrophy Phenotype in Childhood-Onset Essential Hypertension.儿童期原发性高血压的左心室肥厚表型
J Clin Hypertens (Greenwich). 2016 May;18(5):449-55. doi: 10.1111/jch.12708. Epub 2015 Oct 5.
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J Hypertens. 2015 Jun;33(6):1182-92. doi: 10.1097/HJH.0000000000000552.
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Congenit Heart Dis. 2015 Jul-Aug;10(4):E164-71. doi: 10.1111/chd.12249. Epub 2015 Jan 20.
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