Akram Iram, Ulrik Charlotte Suppli, Johnsen Claus Rikard
Ugeskr Laeger. 2016 Jun 27;178(26).
Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least due to suboptimal adherence with controller therapy and pregnant women's concerns about harmful effects of medication on the fetus. This review provides an update on the safety of asthma medication during pregnancy, based on recent clinical studies and international guidelines.
哮喘是妊娠期最常见的慢性疾病之一。孕期哮喘得到良好控制可降低病情加重的风险,进而降低不良妊娠结局的风险。对患有哮喘的孕妇进行药物治疗是一项挑战,尤其是因为患者对控制治疗的依从性欠佳,以及孕妇担心药物对胎儿产生有害影响。本综述基于近期临床研究和国际指南,对孕期哮喘用药的安全性进行了更新。