Beyth R J, Alguire P C
Department of Medicine, Michigan State University, East Lansing 48824-1315.
Postgrad Med. 1989 Jul;86(1):229-32. doi: 10.1080/00325481.1989.11704339.
The case reported here demonstrates the importance of considering the possibility of occult malignancy in young patients presenting with extensive or migratory thromboses in atypical locations that appear resistant to standard therapy. Suspicion for malignancy-related thrombosis is heightened by the absence of known precipitating causes and by a negative family history of thrombosis. The search for the responsible underlying neoplasm can be frustrating, but diagnosis and successful treatment of the tumor remain the keys to controlling the abnormal thrombotic state.
本文报道的病例表明，对于年轻患者出现非典型部位广泛或游走性血栓且对标准治疗耐药时，考虑隐匿性恶性肿瘤的可能性非常重要。已知促发因素的缺乏以及血栓形成的家族史阴性会增加对恶性肿瘤相关血栓形成的怀疑。寻找潜在的肿瘤可能令人沮丧，但肿瘤的诊断和成功治疗仍然是控制异常血栓形成状态的关键。
