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Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer.AGO卵巢委员会声明:国际妇产科联盟(FIGO)和世界卫生组织(WHO)关于卵巢癌、输卵管癌和原发性腹膜癌的新分类
Geburtshilfe Frauenheilkd. 2015 Oct;75(10):1021-1027. doi: 10.1055/s-0035-1558079.
2
Surgical staging and prognosis in serous borderline ovarian tumours (BOT): a subanalysis of the AGO ROBOT study.浆液性卵巢交界性肿瘤(BOT)的手术分期与预后:AGO ROBOT研究的亚分析
Br J Cancer. 2015 Feb 17;112(4):660-6. doi: 10.1038/bjc.2014.648. Epub 2015 Jan 6.
3
Mucinous tumors of the ovary: current thoughts on diagnosis and management.卵巢黏液性肿瘤:关于诊断与治疗的当前观点
Curr Oncol Rep. 2014 Jun;16(6):389. doi: 10.1007/s11912-014-0389-x.
4
Age-dependent differences in borderline ovarian tumours (BOT) regarding clinical characteristics and outcome: results from a sub-analysis of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) ROBOT study.年龄相关的交界性卵巢肿瘤(BOT)的临床特征和结局差异:来自 Arbeitsgemeinschaft Gynaekologische Onkologie(AGO)ROBOT 研究的子分析结果。
Ann Oncol. 2014 Jul;25(7):1320-1327. doi: 10.1093/annonc/mdu119. Epub 2014 Mar 11.
5
Borderline ovarian tumors: a study of 100 cases from a Tertiary Care Hospital.交界性卵巢肿瘤:来自一家三级护理医院的100例病例研究。
Contemp Oncol (Pozn). 2013;17(3):307-10. doi: 10.5114/wo.2013.34635. Epub 2013 Jun 28.
6
Mucinous borderline tumours of the ovary and the appendix: a retrospective study and overview of the literature.卵巢和阑尾的黏液性交界性肿瘤:一项回顾性研究和文献综述。
Gynecol Oncol. 2014 May;133(2):155-8. doi: 10.1016/j.ygyno.2014.02.013. Epub 2014 Feb 16.
7
Epidemiologic features of borderline ovarian tumors in California: a population-based study.加利福尼亚州交界性卵巢肿瘤的流行病学特征:一项基于人群的研究。
Cancer Causes Control. 2013 Apr;24(4):665-74. doi: 10.1007/s10552-013-0145-9. Epub 2013 Jan 13.
8
Borderline ovarian tumors: features and controversial aspects.交界性卵巢肿瘤:特征与争议点。
Eur J Obstet Gynecol Reprod Biol. 2013 Mar;167(1):86-9. doi: 10.1016/j.ejogrb.2012.11.002. Epub 2012 Dec 5.
9
Pathology of cancers of the female genital tract.女性生殖道癌症的病理学
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Long-term outcomes following conservative surgery for borderline tumor of the ovary: a large population-based study.卵巢交界性肿瘤保守性手术后的长期结局:一项基于大人群的研究。
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黏液性卵巢交界性肿瘤:来自单一中心的75例患者分析。

Mucinous borderline ovarian tumors: Analysis of 75 patients from a single center.

作者信息

Cömert Duygu Kavak, Üreyen Işın, Karalok Alper, Taşçı Tolga, Türkmen Osman, Öcalan Reyhan, Turan Taner, Tulunay Gökhan

机构信息

Department of Obstetrics and Gynecology, Ankara Training and Research Hospital, Ankara, Turkey.

Department of Obstetrics and Gynecology, Etlik Zübeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey.

出版信息

J Turk Ger Gynecol Assoc. 2016 Jan 12;17(2):96-100. doi: 10.5152/jtgga.2016.15208. eCollection 2016.

DOI:10.5152/jtgga.2016.15208
PMID:27403076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4922732/
Abstract

OBJECTIVE

To analyze the clinicopathologic features, recurrence and survival rates, reproductive history, and treatment of patients with mucinous borderline ovarian tumors (mBOTs).

MATERIAL AND METHODS

Patients with a diagnosis of mBOT were evaluated retrospectively. Patients with borderline ovarian tumors other than mucinous type and concomitant invasive cancer were excluded.

RESULTS

A total of 75 patients were identified. Median age was 38 years. The most common symptom was pain (42.7%). Median CA-125 level was 23.5 IU/mL (range, 1-809 IU/mL). Median tumor size was 200 mm (range, 40-400 mm), and 6.7% of mBOTs were bilateral. Thirty-six (48%) patients underwent staging surgery. Two patients (5.9%) had nodal involvement. One patient received platinum-based adjuvant chemotherapy. One (1.3%) patient had recurrence. None of the patients died because of the ovarian tumor. A total of 43 patients had conservative surgery.

CONCLUSION

Prognosis of mBOTs is excellent, and fertility-sparing surgery should be considered in the reproductive age group. Furthermore, the necessity of staging surgery is controversial.

摘要

目的

分析黏液性交界性卵巢肿瘤(mBOTs)患者的临床病理特征、复发率和生存率、生育史及治疗情况。

材料与方法

对诊断为mBOTs的患者进行回顾性评估。排除黏液性以外的其他类型交界性卵巢肿瘤及合并浸润性癌的患者。

结果

共纳入75例患者。中位年龄为38岁。最常见症状为疼痛(42.7%)。CA-125中位水平为23.5 IU/mL(范围1 - 809 IU/mL)。肿瘤中位大小为200 mm(范围40 - 400 mm),6.7%的mBOTs为双侧性。36例(48%)患者接受了分期手术。2例(5.9%)患者有淋巴结受累。1例患者接受了铂类辅助化疗。1例(1.3%)患者复发。无患者因卵巢肿瘤死亡。共43例患者接受了保留生育功能手术。

结论

mBOTs预后良好,生育年龄组患者应考虑保留生育功能手术。此外,分期手术的必要性存在争议。