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胰岛素治疗的心理障碍:青春期女性比男性更担忧。

Psychological barriers to optimal insulin therapy: more concerns in adolescent females than males.

机构信息

Division of Mental Health and Addiction, Regional Department for Eating Disorders, Oslo University Hospital, Oslo, Norway; Oslo Diabetes Research Centre, Oslo University Hospital, Oslo, Norway.

Division of Mental Health and Addiction, Regional Department for Eating Disorders , Oslo University Hospital , Oslo , Norway.

出版信息

BMJ Open Diabetes Res Care. 2016 Jun 23;4(1):e000203. doi: 10.1136/bmjdrc-2016-000203. eCollection 2016.

Abstract

OBJECTIVE

The aim of this study is to investigate psychological barriers (illness perceptions, insulin beliefs, and coping strategies) to optimal insulin therapy among adolescents with type 1 diabetes (T1D), with a specific focus on gender differences and mode of treatment (insulin pump vs pen).

METHODS

A total of 105 males and females (12-20 years) participated in this study. The Brief Illness Perception Questionnaire, the Beliefs about Medicines Questionnaire, and the Adolescent Coping Orientation for Problem Experiences were completed. Additionally, diabetes clinical data were collected by the Norwegian Childhood Diabetes Registry.

RESULTS

Females had significantly more negative illness perceptions than males on all dimensions (p<0.05), with moderate-to-large effect sizes. Regarding insulin beliefs, females scored significantly higher than males on insulin concern (p<0.001), indicating more concerns about insulin. There were no significant gender differences on perceptions of insulin necessity. Finally, females scored significantly higher on the coping strategies being social and solving family problems (p<0.01), indicating more positive coping among females than males for these subscales. In terms of treatment mode, the only statistically significant difference in the psychological aspects was for the illness perception treatment control, with patients using insulin pen reporting more negative perceptions on this dimension than patients using insulin pump.

CONCLUSIONS

Addressing psychological aspects may be a clinically important supplement to standard somatic T1D care. The consistent finding of gender differences across the psychological measures implies that a tailored treatment approach for males and females with T1D may be warranted.

摘要

目的

本研究旨在探讨青少年 1 型糖尿病(T1D)患者接受最佳胰岛素治疗的心理障碍(疾病认知、胰岛素信念和应对策略),特别关注性别差异和治疗方式(胰岛素泵与笔)。

方法

共有 105 名 12-20 岁的男性和女性参与了这项研究。他们完成了简短疾病认知问卷、药物信念问卷和青少年应对问题体验取向问卷。此外,糖尿病临床数据由挪威儿童糖尿病登记处收集。

结果

女性在所有维度上的疾病认知均显著比男性更消极(p<0.05),具有中到大的效应量。在胰岛素信念方面,女性在胰岛素担忧方面的得分显著高于男性(p<0.001),表明对胰岛素的担忧更多。在对胰岛素必要性的认知方面,男女之间没有显著的性别差异。最后,女性在应对社交和解决家庭问题方面的得分显著更高(p<0.01),表明女性在这些子量表上的应对方式比男性更积极。在治疗方式方面,心理方面唯一具有统计学意义的差异是在疾病认知治疗控制方面,使用胰岛素笔的患者在这一维度上的认知更消极,而使用胰岛素泵的患者则没有。

结论

关注心理方面可能是标准躯体 T1D 护理的重要临床补充。在心理测量方面一致存在性别差异的发现表明,T1D 患者可能需要针对男性和女性的个性化治疗方法。

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