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儿童胆囊弥漫性腺肌增生症

Diffuse Adenomyomatosis of the Gallbladder in a Child.

作者信息

Eroğlu Nilgün, Erduran Erol, İmamoğlu Mustafa, Sağnak Zeynep, Cansu Ayşegül

机构信息

Departments of *Pediatric Hematology and Oncology †Pediatric Surgery ‡Pathology §Radiogical, Karadeniz Technical University, Trabzon, Turkey.

出版信息

J Pediatr Hematol Oncol. 2016 Nov;38(8):e307-e309. doi: 10.1097/MPH.0000000000000640.

Abstract

Adenomyomatosis of the gallbladder (ADMG) is characterized by proliferation of the mucosal epithelium and hypertrophy of the muscularis. ADMG is predominantly diagnosed by using ultrasonography. Although ADMG is benign in nature, lithiasis, and chronic inflammation secondary to it may lead to dysplastic changes and cancer. Mucosal invagination through the hypertrophied muscularis results in large intramural diverticula or sinus tracts which are visible at radiology, known as Rokitansky-Aschoff sinuses. Histologically, ADMG manifests with hyperplasia of the muscular layer and proliferation of mucosal glandular tissues. We describe a case of ADMG in an 8-year-old girl presenting with recurrent abdominal pain. Diagnosis was made using ultrasound, and the condition was successfully treated with open cholecystectomy. Ultrasound scanning in children presenting with recurrent abdominal pain may lead to more accurate diagnosis of ADMG during childhood.

摘要

胆囊腺肌增生症(ADMG)的特征是黏膜上皮增生和肌层肥厚。ADMG主要通过超声检查来诊断。尽管ADMG本质上是良性的,但结石及其继发的慢性炎症可能导致发育异常改变和癌症。黏膜通过肥厚的肌层内陷形成大的壁内憩室或窦道,在放射学上可见,称为罗-阿窦。组织学上,ADMG表现为肌层增生和黏膜腺组织增殖。我们描述了一例8岁反复腹痛女童的ADMG病例。通过超声检查做出诊断,并通过开腹胆囊切除术成功治疗了该疾病。对反复腹痛的儿童进行超声扫描可能会在儿童期更准确地诊断ADMG。

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