Loprinzi Paul D
Center for Health Behavior Research, Department of Health, Exercise Science, and Recreation Management, The University of Mississippi, University, MS, USA
Am J Health Promot. 2016 May;30(5):331-4. doi: 10.1177/0890117116646340.
Studies have examined the independent and additive effects of health behaviors (e.g., physical activity, diet, sleep, and smoking) on systemic inflammation, but we know little about whether different pairs of these behaviors differentially influence inflammation, which was the purpose of this study.
Cross-sectional.
The National Health and Nutrition Examination Survey (NHANES) 2005-2006.
A total of 2051 adults (≥20 years).
A questionnaire/interview was used to assess sleep and dietary behavior; physical activity was assessed via accelerometry; smoking was assessed via cotinine levels; and a blood sample was taken to assess systemic inflammation (C-reactive protein; [CRP]).
Multivariable linear regression analysis.
Six health behavior pairs were evaluated: (1) active and healthy diet, (2) active and adequate sleep, (3) active and nonsmoker, (4) healthy diet and adequate sleep, (5) healthy diet and nonsmoker, and (6) adequate sleep and nonsmoker. After adjusting for age, gender, race-ethnicity, poverty level, and chronic disease, only active and nonsmoker (β = -.15) and healthy diet and adequate sleep (β = -.16) were associated with CRP.
Regular physical activity and smoking avoidance and healthy eating and adequate sleep were the two health behavior pairs associated with less inflammation. This suggests that certain health behaviors may act synergistically on reducing systemic inflammation, whereas other health behavior combinations may not. Such knowledge may help to develop and implement tailored health behavior interventions.
已有研究探讨了健康行为（如体育活动、饮食、睡眠和吸烟）对全身炎症的独立和累加效应，但我们对这些行为的不同组合是否会对炎症产生不同影响知之甚少，而这正是本研究的目的。
横断面研究。
2005 - 2006年美国国家健康与营养检查调查（NHANES）。
共2051名成年人（≥20岁）。
采用问卷/访谈评估睡眠和饮食行为；通过加速度计评估体育活动；通过可替宁水平评估吸烟情况；采集血样评估全身炎症（C反应蛋白；[CRP]）。
多变量线性回归分析。
评估了六组健康行为组合：（1）积极运动与健康饮食，（2）积极运动与充足睡眠，（3）积极运动与不吸烟，（4）健康饮食与充足睡眠，（5）健康饮食与不吸烟，以及（6）充足睡眠与不吸烟。在调整了年龄、性别、种族、贫困水平和慢性病因素后，只有积极运动与不吸烟（β = -0.15）以及健康饮食与充足睡眠（β = -0.16）与CRP相关。
规律的体育活动、避免吸烟以及健康饮食和充足睡眠是与炎症减轻相关的两组健康行为组合。这表明某些健康行为可能在减轻全身炎症方面具有协同作用，而其他健康行为组合可能并非如此。这些知识可能有助于制定和实施有针对性的健康行为干预措施。
