Habara Maoto, Tsuchikane Etsuo, Nasu Kenya, Kinoshita Yoshihisa, Yaguchi Tomonori, Suzuki Yoriyasu, Matsuo Hitoshi, Terashima Mitsuyasu, Matsubara Tetsuo, Suzuki Takahiko
Department of Cardiovascular Medicine, Toyohashi Heart Center, Aichi, Japan.
Department of Cardiovascular Medicine, Nagoya Heart Center, Aichi, Japan.
Catheter Cardiovasc Interv. 2017 Apr;89(5):880-887. doi: 10.1002/ccd.26627. Epub 2016 Jul 12.
Despite development of drug eluting stents (DES), percutaneous coronary intervention (PCI) for bifurcation lesions using DES alone remains challenging. The aim of this study was to report on the initial clinical experience with a novel directional coronary atherectomy (DCA) catheter.
Patients with de novo bifurcation lesions were entered into a prospective registry and a novel DCA catheter was used. Device, procedural success and in-hospital outcomes were evaluated. A total of 14 patients with bifurcation lesions were enrolled. DCA was performed successfully in all cases without any major procedure-related events (device success rate: 100%, procedural success rate: 100%). Four patients (29%) were treated without stent implantation and simple stenting was achieved in the other 10 patients. No in-hospital major adverse cardiac event was observed.
PCI with a novel DCA catheter for bifurcation lesions may be safe and effective. The clinical significance of these findings needs to be determined in future studies. This study was performed to evaluate the safety and efficacy of a novel directional coronary atherectomy catheter for bifurcation lesions. Both the device and procedural success rates were 100%. Complex stenting could be avoided in all cases. No inhospital major adverse cardiac event was observed. The novel directional coronary atherectomy catheter may be safe and effective for bifurcation lesions, even in this drug eluting stent era. © 2016 Wiley Periodicals, Inc.
尽管药物洗脱支架（DES）已得到发展，但仅使用DES对分叉病变进行经皮冠状动脉介入治疗（PCI）仍具有挑战性。本研究的目的是报告一种新型定向冠状动脉斑块旋切术（DCA）导管的初步临床经验。
将新发分叉病变患者纳入前瞻性登记研究，并使用一种新型DCA导管。评估了器械、手术成功率和住院期间的结果。共纳入14例分叉病变患者。所有病例均成功进行了DCA，未发生任何与手术相关的重大事件（器械成功率：100%，手术成功率：100%）。4例患者（29%）未植入支架，其余10例患者进行了简单支架置入。未观察到住院期间的重大不良心脏事件。
使用新型DCA导管对分叉病变进行PCI可能是安全有效的。这些发现的临床意义需要在未来的研究中确定。本研究旨在评估一种新型定向冠状动脉斑块旋切术导管对分叉病变的安全性和有效性。器械和手术成功率均为100%。所有病例均可避免复杂的支架置入。未观察到住院期间的重大不良心脏事件。即使在这个药物洗脱支架时代，新型定向冠状动脉斑块旋切术导管对分叉病变可能也是安全有效的。©2016威利期刊公司
