Berriche S, David F, Lucotte G
Laboratoire de Génétique Moléculaire de l'INTS, Paris.
Rev Neurol (Paris). 1989;145(5):401-5.
We analyzed the segregation between fragile site Xq 27 and flanking polymorphic probes (52A, for factor 9, 4D-8, for factor 8, St14 and MN12) in a great Xq-fra pedigree. On the basis of these data, the use of these probes is discussed in view of its value as a diagnostic tool.
我们在一个大型Xq脆性位点家系中分析了脆性位点Xq 27与侧翼多态性探针（用于因子IX的52A、用于因子VIII的4D - 8、St14和MN12）之间的分离情况。基于这些数据，鉴于其作为诊断工具的价值，对这些探针的应用进行了讨论。
