神经管缺陷的产前诊断
PRENATAL DIAGNOSIS OF NEURAL TUBE DEFECTS.
作者信息
Gupta S G, Singh H
机构信息
Medical Officer (Radiodiagnosis), Command Hospital (Southern Command) Pune - 411 040.
Senior Advisor (Radiodiagnosis), Command Hospital (Southern Command) Pune - 411 040.
出版信息
Med J Armed Forces India. 2001 Apr;57(2):126-8. doi: 10.1016/S0377-1237(01)80130-1. Epub 2011 Jul 21.
14 cases of neural tube defect (NTD) were detected on screening of 1950 pregnant women over a period of 30 months by antenatal ultrasonography (USG) examination, suggesting an incidence of 7.1 per thousand conceptions. The distribution of types of NTD were occult dysraphism 14%, meningocele 14%, myelocele 7%, myelomeningocele 14%, encephalocele 14% and anencephaly 37%. The study established high accuracy of USG screening for antenatal diagnosis of NTD with sensitivity of 85.71% and specificity of 100.
在30个月的时间里，通过产前超声检查（USG）对1950名孕妇进行筛查，发现14例神经管缺陷（NTD），提示每千次妊娠的发病率为7.1。NTD类型的分布为隐性脊柱裂14%、脊膜膨出14%、脊髓膨出7%、脊髓脊膜膨出14%、脑膨出14%和无脑儿37%。该研究证实了USG筛查对NTD产前诊断具有较高的准确性，敏感性为85.71%，特异性为100。
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