Malde Sachin, Sihra Néha, Naaseri Sahar, Spilotros Marco, Solomon Eskinder, Pakzad Mahreen, Hamid Rizwan, Ockrim Jeremy L, Greenwell Tamsin J
Department of Urology, University College London Hospital, London, UK.
Department of Radiology, University College London Hospital, London, UK.
BJU Int. 2017 Jan;119(1):158-163. doi: 10.1111/bju.13579. Epub 2016 Aug 17.
To assess the presenting features and medium-term symptomatic outcomes in women having excision of urethral diverticulum with Martius labial fat pad (MLFP) interposition.
We reviewed our prospective database of all female patients having excision of a symptomatic urethral diverticulum between 2007 and 2015. Data on demographics, presenting symptoms and clinical features were collected, as well as postoperative outcomes.
In all, 70 women with a mean (range) age of 46.5 (24-77) years underwent excision of urethral diverticulum with MLFP interposition. The commonest presenting symptoms were a urethral mass (69%), urethral pain (61%), and dysuria (57%). Pre-existing stress urinary incontinence (SUI) was present in 41% (29) of the women. After surgery, at a mean (SD) of 18.9 (16.4) months follow-up (median 14 months), complete excision of urethral diverticulum was achieved in all the women, with resolution of urethral mass, dysuria and dyspareunia in all, and urethral pain in 81%. Immediately after surgery, 10 (24%) patients reported de novo SUI, which resolved with time and pelvic floor muscle training such that at 12 months only five (12%) reported continued SUI. There was one symptomatic diverticulum recurrence (1.4%).
The commonest presenting symptom of a female urethral diverticulum is urethral pain followed by dysuria and dyspareunia. Surgical excision with MLFP interposition results in complete resolution of symptoms in most women. The incidence of persistent de novo SUI in an expert high-volume centre is 12%.
评估采用Martius阴唇脂肪垫(MLFP)置入术切除尿道憩室的女性患者的临床表现及中期症状转归。
我们回顾了2007年至2015年间所有有症状尿道憩室切除的女性患者的前瞻性数据库。收集了人口统计学、临床表现和临床特征数据以及术后转归。
共有70名平均(范围)年龄为46.5(24 - 77)岁的女性接受了MLFP置入术切除尿道憩室。最常见的临床表现为尿道肿物(69%)、尿道疼痛(61%)和排尿困难(57%)。41%(29名)女性术前存在压力性尿失禁(SUI)。术后,平均(标准差)随访18.9(16.4)个月(中位数14个月),所有女性均实现了尿道憩室的完全切除,尿道肿物、排尿困难和性交困难均消失,81%的患者尿道疼痛消失。术后即刻,10名(24%)患者报告出现新发SUI,随着时间推移及盆底肌训练,至12个月时仅有5名(12%)患者报告仍存在SUI。有1例症状性憩室复发(1.4%)。
女性尿道憩室最常见的临床表现是尿道疼痛,其次是排尿困难和性交困难。采用MLFP置入术的手术切除可使大多数女性症状完全缓解。在一家专家级大容量中心,新发持续性SUI的发生率为12%。