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女性尿道憩室患者尿动力学压力性尿失禁的发生率和结局。

The incidence and outcomes of urodynamic stress urinary incontinence in female patients with urethral diverticulum.

机构信息

Department of Urology, UCLH, London, UK.

Department of Urology, Guys and St Thomas' NHS Foundation Trust, London, UK.

出版信息

Neurourol Urodyn. 2019 Sep;38(7):1889-1900. doi: 10.1002/nau.24090. Epub 2019 Jul 3.

Abstract

AIMS

To assess the incidence and management of urodynamic stress urinary incontinence (USUI) in women undergoing transvaginal excision of a urethral diverticulum (UD) at our institution.

METHODS

A prospective database, capturing patients undergoing urethral diverticulectomy over a 9-year period (May 2007 to August 2016), was reviewed focusing on USUI and subsequent management.

RESULTS

One hundred patients underwent UD excision (with modified Martius labial fat-pad flap interposition). Preoperative magnetic resonance imaging data, available in 90 patients, demonstrated that 80% had complex diverticula. Complete urodynamic data were available for 93 patients. Preoperatively, 27 patients (29%) had USUI of which 16 patients resolved with either UD excision alone (n = 8) or 3 months of pelvic floor muscle therapy (PFMT) (n = 8). All 11 with persistent postoperative USUI had video urodynamics (VUDs) confirming Blaivas type 3 USUI. Six patients had a rectus fascial pubovaginal sling (RFPVS) with success in five (83.3%) while five had a mid-urethral obturator tape (MUT-O) with 100% success. Sixteen patients developed de novo stress urinary incontinence (SUI) postoperatively, with resolution after PFMT in 12 (75%). VUDS identified USUI (Blaivas type 3) in two (of the remaining four) patients, managed successfully with MUT-O (n = 1) and RFPVS (n = 1).

CONCLUSION

Preoperative USUI is present in 29% with UD. Postoperatively, 35.5% (n = 33) have pre-existing (19) or de novo (14) SUI, of which 60.6% (n = 20) resolves after 12 months of conservative management. Surgery for USUI is required in 13 (13.9%), with cure in 92.3%. This supports our practice to excise UD primarily and delay USUI surgery, therefore, avoiding overtreatment for the majority.

摘要

目的

评估本机构经阴道切除尿道憩室(UD)的女性患者中尿动力学压力性尿失禁(USUI)的发生率和处理方法。

方法

对 9 年来(2007 年 5 月至 2016 年 8 月)接受尿道憩室切除术的患者前瞻性数据库进行回顾性分析,重点关注 USUI 及其后续处理。

结果

100 例患者接受 UD 切除术(采用改良的 Martius 阴唇脂肪垫皮瓣间置术)。90 例患者术前磁共振成像(MRI)数据显示,80%为复杂憩室。93 例患者均行完整尿动力学检查。术前 27 例(29%)有 USUI,其中 16 例患者单独切除 UD(n=8)或接受 3 个月盆底肌治疗(PFMT)(n=8)后治愈。所有 11 例术后持续性 USUI 患者均行视频尿动力学检查(VUD),证实 Blaivas 3 型 USUI。6 例患者行耻骨直肠筋膜阴道悬吊带术(RFPVS),5 例(83.3%)成功;5 例行中尿道闭合器吊带术(MUT-O),均成功。术后 16 例新发压力性尿失禁(SUI),12 例(75%)经 PFMT 治愈。VUD 检查发现 2 例(4 例中的 2 例)患者存在 USUI(Blaivas 3 型),均成功采用 MUT-O(n=1)和 RFPVS(n=1)治疗。

结论

UD 患者术前 USUI 发生率为 29%。术后 35.5%(n=33)存在术前(19 例)或新发(14 例)SUI,其中 60.6%(n=20)经 12 个月保守治疗后缓解。13 例(13.9%)患者需要手术治疗 USUI,治愈率为 92.3%。这支持我们的实践,即主要切除 UD,延迟 USUI 手术,从而避免对大多数患者过度治疗。

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