Bayhan Gülsüm İclal, Tanır Gönül, Metin Özge, Şimsek Hülya, Aydın Teke Türkan, Öz Fatma Nur, Gayretli Aydın Zeynep Gökçe
Division of Pediatric Infectious Disease, Department of Pediatrics, Yuzuncu Yıl University, Faculty of Medicine, Van, Turkey.
Turk J Pediatr. 2015 Sep-Oct;57(5):431-8.
The purpose of this study was to evaluate the clinical, radiological, microbiological characteristics, side effects of anti-TB drugs and treatment outcome of childhood definite or probable TB. The medical records of all childhood TB patients were investigated in the department of pediatric infectious disease of a tertiary care hospital between January 2005 and December 2012. Patients who followed-up until the anti-TB treatment was completed were included in the study. One hundred forty four pediatric cases with active TB were included in the study (27 definite, 117 probable). Twenty-four (16.7 %) patients were asymptomatic at admission. Pulmonary TB was the most common type. The most common localizations for extrapulmonary TB were superficial lymphadenitis. An index case was detected in 39.6% of the patients. In conclusion, the absence of constitutional symptoms does not exclude TB. Household contact screening plays an important role in the diagnosis of childhood TB especially in asymptomatic patients.
本研究的目的是评估儿童确诊或疑似结核病的临床、放射学、微生物学特征、抗结核药物的副作用及治疗结果。2005年1月至2012年12月期间，在一家三级护理医院的儿科传染病科对所有儿童结核病患者的病历进行了调查。纳入研究的患者为接受抗结核治疗直至完成随访的患者。本研究纳入了144例活动性结核病患儿（27例确诊，117例疑似）。24例（16.7%）患者入院时无症状。肺结核是最常见的类型。肺外结核最常见的部位是浅表淋巴结炎。39.6%的患者检测到索引病例。总之，无全身症状并不排除结核病。家庭接触者筛查在儿童结核病诊断中起着重要作用，尤其是在无症状患者中。
