Guarracino Alessandro, Lacitignola Luca, Auriemma Edoardo, De Monte Valentina, Grasso Salvatore, Crovace Antonio, Staffieri Francesco
Dipartimento delle Emergenze e Trapianti di Organo, Università degli Studi di Bari "Aldo Moro," sezione Cliniche Veterinarie e P.A, Valenzano.
Istituto Veterinario di Novara.
Vet Radiol Ultrasound. 2016 Sep;57(5):475-81. doi: 10.1111/vru.12388. Epub 2016 Jul 14.
This randomized controlled trial study aimed to identify the optimal positive pressure (PP) level that can clear atelectasis while avoiding pulmonary hyperinflation during the breath-hold technique in dogs undergoing thoracic computed tomography (CT). Sixty dogs affected by mammary tumors undergoing thoracic CT for the screening of pulmonary metastases were randomly assigned to six groups with different levels of PP during the breath-hold technique: 0 (control), 5 (PP5), 8 (PP8), 10 (PP10), 12 (PP12), and 15 (PP15) cmH2 O. The percentage of atelectatic lung region was lower in the PP10 (3.7 ± 1.1%; P = 0.002), PP12 (3.4 ± 1.3%; P = 0.0001), and PP15 (2.8 ± 0.9%; P = 0.006) groups than in the control group (5.0 ± 2.3%), and the percentage of poorly aerated lung region was lower in the PP8 (15.1 ± 2.6%; P = 0.0009), PP10 (13.0 ± 2.0 %; P = 0.002), PP12 (13.0 ± 2.2 %; P = 0.0002), and PP15 (11.1 ± 1.9%; P = 0.0002) groups than in the control group (19.8 ± 5.0). The percentage of normally aerated lung region, however, was higher in the PP10 (79.7 ± 4.1%; P = 0.005), PP12 (79.8 ± 5.1%; P = 0.0002), and PP15 (80.2 ± 4.9%; P = 0.002) groups than in the control group (73.4 ± 6.6%). A PP of 10-12 cmH2 O during the breath-hold technique should be considered to improve lung aeration during a breath-hold technique in dogs undergoing thoracic CT.
这项随机对照试验旨在确定在接受胸部计算机断层扫描（CT）的犬类屏气技术过程中，能够消除肺不张同时避免肺过度充气的最佳正压（PP）水平。60只患有乳腺肿瘤并接受胸部CT以筛查肺转移的犬被随机分为六组，在屏气技术过程中给予不同水平的PP：0（对照组）、5（PP5）、8（PP8）、10（PP10）、12（PP12）和15（PP15）cmH₂O。PP10组（3.7±1.1%；P = 0.002）、PP12组（3.4±1.3%；P = 0.0001）和PP15组（2.8±0.9%；P = 0.006）的肺不张区域百分比低于对照组（5.0±2.3%），PP8组（15.1±2.6%；P = 0.0009）、PP10组（13.0±2.0%；P = 0.002）、PP12组（13.0±2.2%；P = 0.0002）和PP15组（11.1±1.9%；P = 0.0002）的通气不良肺区域百分比低于对照组（19.8±5.0）。然而，PP10组（79.7±4.1%；P = 0.005）、PP12组（79.8±5.1%；P = 0.0002）和PP15组（80.2±4.9%；P = 0.002）的正常通气肺区域百分比高于对照组（73.4±6.6%）。在接受胸部CT的犬类屏气技术过程中，应考虑在屏气技术期间使用10 - 12 cmH₂O的PP来改善肺通气。
