Shleĭkin A G, Gor'kova L B, Pozhilenkova K S, Zvezdochkin A G
Vopr Med Khim. 1989 Mar-Apr;35(2):86-9.
Blood plasma of healthy persons bound 13.13 +/- 1.07 mmol/l of p-phenylene diamine (PDA), histamine pectic index constituted 33.3 +/- 2.18%. In patients with neurodermitis and eczema both these patterns were markedly reduced. Unitiol (10(-3) mol/l) increased PDA binding and histamine level in vitro. The same concentration of cystamine decreased histamine pectic index in healthy persons. Importance of protein SH-groups in binding of amines is discussed.
健康人的血浆结合对苯二胺(PDA)的量为13.13±1.07 mmol/l,组胺果胶指数为33.3±2.18%。在神经性皮炎和湿疹患者中,这两种指标均显著降低。依地醇(10⁻³ mol/l)在体外可增加PDA结合量和组胺水平。相同浓度的胱胺可降低健康人的组胺果胶指数。文中讨论了蛋白质SH基团在胺类结合中的重要性。