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[口服钙负荷对复发性钙肾结石和高钙尿症患者血清镁浓度及其尿排泄的影响——鉴别诊断潜力]

[The effect of oral calcium loading on the serum magnesium concentration and its urinary excretion in patients with recurrent calcium nephrolithiasis and hypercalciuria--differential diagnostic potentials].

作者信息

Ivanov I, Tsachev K

出版信息

Vutr Boles. 1989;28(1):65-70.

PMID:2741443
Abstract

The study deals with 13 healthy controls with normal basic indices for calcium-phosphorus metabolism and 25 patients with recurrent calcium nephrolithiasis and hypercalciuria, 13 of them with renal hypercalciuria and 12 patients with absorptive hypercalciuria. The oral calcium-tolerance test was carried out in all persons. The changes in the serum and urine calcium and magnesium concentrations following the calcium loading are recorder. A statistically significant increase of magnesium urine excretion was found in all persons examined, the highest being in the patients with renal hypercalciuria, considerably higher than in the healthy controls. The conclusion is reached that the magnesium urine excretion gives valuable information for the diagnosis of patients with renal hypercalciuria.

摘要

该研究涉及13名钙磷代谢基本指标正常的健康对照者以及25名复发性钙肾结石和高钙尿症患者,其中13例为肾性高钙尿症患者,12例为吸收性高钙尿症患者。对所有人进行了口服钙耐量试验。记录了钙负荷后血清和尿液中钙和镁浓度的变化。在所有受检者中均发现尿镁排泄有统计学意义的增加,其中肾性高钙尿症患者增加最多,明显高于健康对照者。得出的结论是,尿镁排泄为肾性高钙尿症患者的诊断提供了有价值的信息。

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