Zhigulin V A, Smirnova I Iu, Bredikhin V T, Filippenko N G
Vestn Dermatol Venerol. 1989(3):42-4.
Antipyrine test has been used to assess drug metabolism of the liver in 43 subjects, including 20 patients suffering from eczema and allergic dermatitis. "Rapid" oxidizers predominated among the patients; tissue barrier permeability for the test agent has been increased in eczema patients. These data should be borne in mind when prescribing the drugs that are subjected mainly to oxidizing metabolism, primarily antiinflammatory agents, to patients suffering from allergic dermatoses.
安替比林试验已用于评估43名受试者的肝脏药物代谢情况，其中包括20名湿疹和过敏性皮炎患者。患者中“快速”氧化者占多数；湿疹患者对试验药物的组织屏障通透性增加。在给过敏性皮肤病患者开主要经氧化代谢的药物（主要是抗炎药）时，应牢记这些数据。
