盐与糖：不良组合。
Salt and sugar: Bad company.
作者信息
Wada Jun
机构信息
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
出版信息
J Diabetes Investig. 2017 Jan;8(1):32-33. doi: 10.1111/jdi.12553. Epub 2016 Aug 30.
Abstract
This report shed light to unrecognized mechanism for the hyperglycemia-induced sodium retention. The activation of PPAR?, elevation of serum adiponectin, and subsequent inhibition of SGLT2 may lead to natriuresis and glycosuria and it may be beneficial in hypertensive diabetic patients.
摘要
本报告揭示了高血糖诱导钠潴留的未被认识的机制。过氧化物酶体增殖物激活受体γ（PPARγ）的激活、血清脂联素升高以及随后对钠-葡萄糖协同转运蛋白2（SGLT2）的抑制可能导致尿钠排泄和糖尿，这可能对高血压糖尿病患者有益。
Zotero 插件