Fukunaga Shohei, Matsumoto Kei, Tanno Yudo, Sudo Ko, Uehara Genta, Miyasato Hitoshi, Tsuboi Nobuo, Ogura Makoto, Yokoo Takashi
Nihon Jinzo Gakkai Shi. 2016;58(4):604-9.
A 37-year-old man diagnosed with minimal change nephrotic syndrome at the age of 17, was admitted to hospital with leg pain. He had relapsed nephrotic syndrome and thromboembolism of the right femoral and middle cerebral arteries. He was treated with steroid pulse therapy and thrombectomy. Right lower extremity necrosis developed and a below-knee amputation was performed. His nephrotic syndrome and the amputated lower extremity necrosis subsequently improved. Arterial thrombosis is a rare complication of nephrotic syndrome; however, it is a severe complication. Prophylactic anticoagulation should be considered in patients with an increased risk of thrombosis.
一名37岁男性，17岁时被诊断为微小病变型肾病综合征，因腿部疼痛入院。他患有复发性肾病综合征以及右股动脉和大脑中动脉血栓栓塞。接受了类固醇冲击疗法和血栓切除术治疗。随后出现右下肢坏死并进行了膝下截肢。他的肾病综合征以及截肢后的下肢坏死随后有所改善。动脉血栓形成是肾病综合征的一种罕见并发症；然而，它是一种严重的并发症。对于血栓形成风险增加的患者，应考虑预防性抗凝治疗。
