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伴有显著浆细胞-淋巴细胞浸润的罕见类型脑膜瘤。一项免疫组织化学和组织化学研究。

Uncommon type of meningiomas with conspicuous plasmo-lymphocytic infiltration. An immunohistochemical and histochemical study.

作者信息

Ohmori T, Tabei R, Fukui K, Sadamoto K, Sakaki S

机构信息

Second Department of Pathology, Ehime University School of Medicine, Japan.

出版信息

Acta Pathol Jpn. 1989 Mar;39(3):190-4. doi: 10.1111/j.1440-1827.1989.tb01499.x.

Abstract

Two cases of meningioma revealing conspicuous plasmo-lymphocytic tissue and hyalinized fibrous tissue components are reported. Histopathological examination of the plasmo-lymphocytic infiltration was performed. Both lesions showed polyclonality of plasma cells as revealed by positive reactions for IgG and paraimmunoglobulin kappa- and lambda-light chains, and amyloid infiltration into the fibrous stroma and blood vessel walls. The histochemical and immunohistochemical characteristics of the lesion in relation to its etiology are briefly discussed.

摘要

报告了两例显示明显浆细胞-淋巴细胞组织和玻璃样化纤维组织成分的脑膜瘤病例。对浆细胞-淋巴细胞浸润进行了组织病理学检查。两个病变均显示浆细胞的多克隆性,表现为IgG以及副免疫球蛋白κ和λ轻链呈阳性反应,并且淀粉样蛋白浸润到纤维基质和血管壁中。简要讨论了该病变在病因学方面的组织化学和免疫组织化学特征。

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