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多西他赛治疗转移性激素敏感型前列腺癌:急需降低中性粒细胞减少性发热风险。

Docetaxel for Metastatic Hormone-sensitive Prostate Cancer: Urgent Need to Minimize the Risk of Neutropenic Fever.

机构信息

Division of Hematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.

Division of Hematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.

出版信息

Eur Urol. 2016 Nov;70(5):707-708. doi: 10.1016/j.eururo.2016.06.041. Epub 2016 Jul 12.

DOI:10.1016/j.eururo.2016.06.041
PMID:27417033
Abstract

First-line docetaxel treatment for metastatic castration-sensitive prostate cancer is associated with higher rates of neutropenic fever compared with those with castration-resistant disease, and prophylactic granulocyte colony-stimulating factor should be considered in those harboring risk factors for developing neutropenia.

摘要

一线多西他赛治疗转移性去势敏感性前列腺癌与去势抵抗性疾病相比,中性粒细胞减少性发热的发生率更高,对于存在发生中性粒细胞减少风险因素的患者,应考虑预防性使用粒细胞集落刺激因子。

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Identification and characterization of biomarkers and their functions for docetaxel-resistant prostate cancer cells.多西他赛耐药前列腺癌细胞生物标志物的鉴定、特征及其功能
Oncol Lett. 2019 Sep;18(3):3236-3248. doi: 10.3892/ol.2019.10623. Epub 2019 Jul 16.
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The timing of docetaxel initiation in metastatic castrate-sensitive prostate cancer and the rate of chemotherapy-induced toxicity.
多西他赛起始治疗转移性去势敏感性前列腺癌的时机和化疗诱导毒性的发生率。
Med Oncol. 2019 Jan 21;36(2):18. doi: 10.1007/s12032-018-1238-9.
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PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy.PrLZ 通过抑制 LKB1/AMPK 介导的自噬增加前列腺癌多西他赛耐药性。
Theranostics. 2018 Jan 1;8(1):109-123. doi: 10.7150/thno.20356. eCollection 2018.
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Treatment of metastatic prostate cancer after STAMPEDE.STAMPEDE研究后转移性前列腺癌的治疗
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