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静脉注射替加环素有助于在标准治疗失败后治愈严重艰难梭菌感染(CDI):1例病例报告及替加环素用于CDI的文献综述

Intravenous Tigecycline Facilitates Cure of Severe Clostridium difficile Infection (CDI) After Failure of Standard Therapy: A Case Report and Literature Review of Tigecycline Use in CDI.

作者信息

Navalkele Bhagyashri D, Lerner Stephen A

机构信息

Division of Infectious Diseases , Wayne State University School of Medicine, Harper University Hospital , Detroit, Michigan.

出版信息

Open Forum Infect Dis. 2016 May 12;3(2):ofw094. doi: 10.1093/ofid/ofw094. eCollection 2016 Apr.

Abstract

Standard treatment for severe Clostridium difficile infection (CDI) is oral vancomycin with metronidazole. After failure of this standard regimen, treatment becomes challenging. A young woman treated for septic shock developed CDI. Standard treatment failed and she was ineligible for fecal transplant. Addition of tigecycline to her regimen resulted in cure.

摘要

严重艰难梭菌感染(CDI)的标准治疗方法是口服万古霉素加甲硝唑。在这种标准治疗方案失败后,治疗变得具有挑战性。一名因感染性休克接受治疗的年轻女性患上了CDI。标准治疗失败,且她不符合粪便移植的条件。在她的治疗方案中加用替加环素后治愈。

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