Chruzander Charlotte, Tinghög Petter, Ytterberg Charlotte, Widén Holmqvist Lotta, Alexanderson Kristina, Hillert Jan, Johansson Sverker
Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, SE - 141 83 Stockholm, Sweden; Department of Physiotherapy, Karolinska University Hospital, SE - 141 86 Stockholm, Sweden.
Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE - 171 77 Stockholm, Sweden; Red Cross University College, SE - 114 28 Stockholm, Sweden.
J Neurol Sci. 2016 Aug 15;367:319-25. doi: 10.1016/j.jns.2016.05.055. Epub 2016 Jun 12.
Even though it is well known that disability due to MS is highly associated with employment status, the long-term longitudinal perspective on sickness absence and disability pension over the MS trajectory is lacking. In addition, further knowledge of risk factors for future disability pension is needed.
To explore long-term longitudinal changes in the prevalence of sickness absence and disability pension in people with MS (PwMS), as well as to explore associations between disease-specific factors, contextual factors and functioning, and the outcome of future full-time disability pension.
A prospective, population-based survival cohort study, with a nine year follow-up, including 114 PwMS was conducted by combining face-to-face collected data and register-based data.
The prevalence of full-time disability pension increased from 20% to 50%, however 24% of the PwMS had no disability pension at all at end of follow-up. Sex, age, disease severity and impaired manual dexterity were associated with future full-time disability pension.
The large increase in prevalence of PwMS on full-time disability pension during the MS trajectory, calls for the development and implementation of evidence-based interventions, aiming at keeping PwMS in the work force. Modifiable factors, such as manual dexterity should be targeted in such interventions.
尽管众所周知,多发性硬化症导致的残疾与就业状况高度相关,但缺乏对多发性硬化症病程中病假和残疾抚恤金的长期纵向研究。此外,还需要进一步了解未来领取残疾抚恤金的风险因素。
探讨多发性硬化症患者(PwMS)病假和残疾抚恤金患病率的长期纵向变化,以及疾病特异性因素、背景因素和功能与未来全职残疾抚恤金结果之间的关联。
通过结合面对面收集的数据和基于登记的数据,对114名PwMS进行了一项前瞻性、基于人群的生存队列研究,随访9年。
全职残疾抚恤金的患病率从20%上升到50%,然而,24%的PwMS在随访结束时根本没有领取残疾抚恤金。性别、年龄、疾病严重程度和手部灵活性受损与未来的全职残疾抚恤金有关。
在多发性硬化症病程中,全职领取残疾抚恤金的PwMS患病率大幅上升,这就需要制定和实施以证据为基础的干预措施,以使PwMS能够继续留在劳动力队伍中。在这类干预措施中,应针对可改变的因素,如手部灵活性。