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应避免用于尿液药物筛查的合成大麻素:对药物依赖应急管理及其他治疗的影响。

Synthetic cannabinoids to avoid urine drug screens: Implications for contingency management and other treatments for drug dependence.

作者信息

Ninnemann Andrew L, Lechner William V, Borges Allison, Lejuez C W

机构信息

University of Maryland, College Park, Department of Psychology, 2103 Cole Student Activities Building, College Park, MD 20742-4411, USA.

Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, USA.

出版信息

Addict Behav. 2016 Dec;63:72-3. doi: 10.1016/j.addbeh.2016.07.004. Epub 2016 Jul 8.

Abstract

Contingency management (CM) is an effective treatment for substance use dependence. Within CM, rewards or vouchers promote continued abstinence by acting as alternative reinforcers to substance use. However, CM relies on the use of accurate biochemical verification methods, such as urinalysis, to verify abstinence. Synthetic cannabinoids (SCs) pose a risk for CM treatment because they are not easily detected by common urinalysis techniques. Although SCs pose a risk, there is limited information regarding current rates of SC use within substance dependent populations as well as rates of substance use and psychiatric disorders among those who use SCs in treatment. We discuss emerging research on these topics and potential implications for CM treatments. Findings suggest CM researchers should test for and query SC use among those being treated for cannabis and cocaine use problems as well as among younger populations of substance users. Implications of other novel psychoactive substances for drug treatment and drug urinalysis are also discussed.

摘要

应急管理(CM)是治疗物质使用依赖的一种有效方法。在应急管理中,奖励或代金券作为物质使用的替代强化物,促进持续戒断。然而,应急管理依赖于使用准确的生化验证方法,如尿液分析,来验证戒断情况。合成大麻素(SCs)给应急管理治疗带来风险,因为它们不容易被常规尿液分析技术检测到。尽管合成大麻素存在风险,但关于物质依赖人群中当前合成大麻素的使用比例,以及在治疗中使用合成大麻素的人群的物质使用和精神障碍发生率,相关信息有限。我们讨论了关于这些主题的新研究以及对应急管理治疗的潜在影响。研究结果表明,应急管理研究人员应该对大麻和可卡因使用问题患者以及年轻物质使用人群进行合成大麻素使用情况的检测和询问。还讨论了其他新型精神活性物质对药物治疗和药物尿液分析的影响。

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