Agrawal Abhinav, Sahni Sonu, Marder Galina, Shah Rakesh, Talwar Arunabh
Monmouth Medical Center, Department of Medicine, 300 s Avenue Long Branch, NJ 07740, USA.
North Shore - Long Island Jewish Health System, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd. Suite 107 New Hyde Park, NY 11040, USA.
Respir Investig. 2016 Jul;54(4):280-3. doi: 10.1016/j.resinv.2016.01.002. Epub 2016 Mar 17.
Spirometry flow-volume measurement is used routinely in the outpatient setting to rule out obstructive lung diseases. Biphasic flow-volume loop is a classic presentation of unilateral bronchial stenosis due to multiple etiologies and it should raise clinical suspicion. Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition with pulmonary manifestations that may be infiltrative (e.g., pneumonia), hemorrhagic, and may rarely cause bronchial stenosis. Herein, we present a case of GPA-related, bronchial obstruction that caused biphasic flow-volume loop along with a literature review.
肺量计流量-容积测量在门诊环境中常用于排除阻塞性肺疾病。双相流量-容积环是多种病因导致的单侧支气管狭窄的典型表现,应引起临床怀疑。肉芽肿性多血管炎(GPA)是一种具有肺部表现的全身性炎症性疾病,其肺部表现可能为浸润性(如肺炎)、出血性,且很少会导致支气管狭窄。在此,我们报告一例与GPA相关的支气管阻塞病例,该病例导致了双相流量-容积环,并进行文献综述。