Vincze Krisztina, Odler Balázs, Müller Veronika
Pulmonológiai Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Diós árok u. 1/C, 1125.
Orv Hetil. 2016 Jul;157(29):1154-60. doi: 10.1556/650.2016.30482.
Systemic lupus erythematosus is the most common connective tissue disease that is associated with pulmonary manifestations. Although lupus has the potential to affect any organ, lung involvement is observed during the course of the disease in most cases and it is prognostic for outcome. Pulmonary manifestations in lupus can be classified into five groups based on the anatomical involvement: pleura, lung parenchyma, bronchi and bronchioli, lung vasculature and respiratory muscles can be involved. The most common respiratory manifestations attributable to lupus are pleuritis with or without pleural effusion, pulmonary vascular disease, upper and lower airway dysfunction, parenchymal disease, and diaphragmatic dysfunction (shrinking lung syndrome). In this article the authors summarize lung involvement of lupus, its diagnosis, therapy and prognosis. Orv. Hetil., 2016, 157(29), 1154-1160.
系统性红斑狼疮是最常见的与肺部表现相关的结缔组织病。尽管狼疮有可能累及任何器官,但在大多数病例中,肺部受累在疾病过程中均可观察到,且对预后有重要意义。狼疮的肺部表现可根据解剖学受累部位分为五类:胸膜、肺实质、支气管和细支气管、肺血管系统以及呼吸肌均可受累。狼疮最常见的呼吸表现为伴有或不伴有胸腔积液的胸膜炎、肺血管疾病、上、下气道功能障碍、实质疾病以及膈肌功能障碍(肺萎陷综合征)。在本文中,作者总结了狼疮的肺部受累情况、诊断、治疗及预后。《匈牙利医学周报》,2016年,157(29),1154 - 1160。