Gülzow H J, Stegmeier K
Dtsch Zahnarztl Z. 1978 Mar;33(3):185-8.
With the help of thin layer chromatography, human saliva was examined after varying lengths of incubation time of radioactively labelled xylitol to determine whether bacteria of the human oral cavity are able to use this sugar substitute. This showed that different activities occur in saliva which either complete the breakdown within a few hours or require more than 24 hours incubation. Induction of the enzymes for xylitol and sorbitol breakdown was observed during incubation, which led to a speeding up of metabolism. A comparison with sorbitol revealed that xylitol is metabolised considerably more slowly than sorbitol.
借助薄层色谱法,在对放射性标记的木糖醇进行不同时长的孵育后,对人类唾液进行了检测,以确定人口腔中的细菌是否能够利用这种糖替代品。结果表明,唾液中出现了不同的活性,有的能在数小时内完成分解,有的则需要超过24小时的孵育。在孵育过程中观察到了木糖醇和山梨醇分解酶的诱导现象,这导致了新陈代谢的加速。与山梨醇的比较显示,木糖醇的代谢速度比山梨醇慢得多。