Santy Lisa, Fierens Johan, Dedrye Lieven
a Department of Internal Medicine, University Hospital Leuven , Leuven , Belgium.
b Department of Abdominal Surgery , Groep Heelkunde-Urologie, Jan Yperman Ziekenhuis , Ieper , Belgium.
Acta Chir Belg. 2016 Jun;116(3):197-200. doi: 10.1080/00015458.2016.1139836. Epub 2016 Apr 21.
Background Brunner's gland hyperplasia is a rare benign tumour and occurs most frequently in the upper part of the duodenum, mostly in the fifth or the sixth decade. Pathogenesis is still unknown. Symptoms are mostly absent, but larger lesions can cause gastric outlet obstruction or bleeding. Biopsies are necessary for differential diagnosis and to rule out cancerous changes. Mostly a resection is required. Methods A case report of a symptomatic Brunneroma is described with a review of the literature. Results: A 72-year-old female presented with melena due to a post-pyloric Brunneroma. After medical work-up a full laparoscopic resection was performed, with an uneventful recovery. Conclusion Brunner's gland hyperplasia is a benign lesion, although malignant transformation has been described. Small pedunculated Brunneromas can be resected endoscopically, but larger lesions need surgical treatment. A full laparoscopic treatment is possible and safe.
背景 布伦纳腺增生是一种罕见的良性肿瘤,最常发生于十二指肠上部,多在50或60岁。发病机制尚不清楚。大多无症状,但较大病变可导致胃出口梗阻或出血。活检对于鉴别诊断和排除癌变是必要的。大多需要进行切除。方法 描述了一例有症状的布伦纳腺瘤病例报告并复习文献。结果:一名72岁女性因幽门后布伦纳腺瘤出现黑便。经医学检查后进行了全腹腔镜切除术,恢复顺利。结论 布伦纳腺增生是一种良性病变,尽管已有恶变的描述。带蒂小布伦纳腺瘤可通过内镜切除,但较大病变需要手术治疗。全腹腔镜治疗是可行且安全的。