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与后路脊柱融合术相关的围手术期并发症:老年医疗保险受益人的研究。

Perioperative Complications Associated With Posterolateral Spine Fusions: A Study of Elderly Medicare Beneficiaries.

机构信息

Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, MD.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA.

出版信息

Spine (Phila Pa 1976). 2018 Jan 1;43(1):16-21. doi: 10.1097/BRS.0000000000001771.

DOI:10.1097/BRS.0000000000001771
PMID:27428388
Abstract

STUDY DESIGN

A retrospective database review.

OBJECTIVE

The aim of this study was to compare the occurrence of complications in patients treated with one to two-level, three to seven-level, and more than eight level fusions.

SUMMARY OF BACKGROUND DATA

Elderly patients constitute a rapidly growing demographic with an increasing need for spinal procedures. Complication rates for spinal surgery in elderly patients range from 37% to 80% with major complications occurring in 12% to 21% of patients.

METHODS

The PearlDiver database (2005-2012) was utilized to compare perioperative complication rates in patients aged 65 years and older undergoing posterolateral fusion of one to two (n = 90,527); three to seven (n = 23,827), and more than eight (n = 2758) thoracolumbar levels. Cohorts were matched by demographics and comorbidities. Ninety-day medical and surgical complication and mortality rates were determined.

RESULTS

In the full, unmatched cohort, the major complication rate was 15.9%, with matched cohorts of one to two, three to seven, and eight-level fusions associated with major complication rates of 12.5%, 20.5%, and 35.4%, respectively. Patients treated with 8+ level fusions had 3.8 and 2.1 times greater odds of developing a major complication than patients treated with 1 to 2 and 3 to 7-level fusions, respectively (P < 0.0001). Patients treated with more than eight-level fusions had 3.9 and 10.8 times increased odds of experiencing mortality than those treated with three to seven-level and one to two-level fusions, respectively.

CONCLUSION

Elderly patients treated with spine fusions spanning more than eight levels experience significantly increased complication rates when compared with patients treated with fusions of shorter length.

LEVEL OF EVIDENCE

摘要

研究设计

回顾性数据库研究。

目的

本研究旨在比较接受 1-2 个节段、3-7 个节段和 8 个以上节段融合的患者并发症的发生情况。

背景资料概要

老年患者是一个快速增长的人群,对脊柱手术的需求也在不断增加。老年患者脊柱手术的并发症发生率为 37%至 80%,其中 12%至 21%的患者发生严重并发症。

方法

利用 PearlDiver 数据库(2005-2012 年)比较年龄在 65 岁及以上的患者行后路融合术的围手术期并发症发生率,融合节段数为 1-2 个(n=90527)、3-7 个(n=23827)和 8 个以上(n=2758)胸腰椎节段。通过人口统计学和合并症对队列进行匹配。确定 90 天内的医疗和手术并发症及死亡率。

结果

在全队列中,严重并发症的发生率为 15.9%,1-2 个、3-7 个和 8 个以上节段融合的匹配队列中,严重并发症的发生率分别为 12.5%、20.5%和 35.4%。与接受 1-2 个和 3-7 个节段融合的患者相比,接受 8 个以上节段融合的患者发生严重并发症的可能性分别高出 3.8 倍和 2.1 倍(P<0.0001)。与接受 3-7 个节段和 1-2 个节段融合的患者相比,接受 8 个以上节段融合的患者死亡的风险分别增加了 3.9 倍和 10.8 倍。

结论

与接受较短节段融合的患者相比,接受 8 个以上节段融合的老年患者并发症发生率显著增加。

证据等级

3 级。

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