Kot Anna, Kenig Jakub, Wałęga Piotr
Pol Przegl Chir. 2016 May 1;88(3):136-41. doi: 10.1515/pjs-2016-0041.
Demographic changes associated with the aging population mean that surgeons increasingly have contact and make decisions about treating patients from the oldest age groups. The aim of the study was to review the literature concerning the treatment of acute appendicitis in patients over the age of 60 years old.
A review of the literature published in the years 2000-2015 has been carried out using the PubMed database. The initial number of results corresponding to the query in English, "appendicitis (MeSH) AND elderly (MeSH)" was 260. Selection based on the titles, abstracts, and eventually whole articles, ultimately resulted in 11 papers concerning the treatment of appendicitis in patients above 60 years of age.
Nine papers were retrospective and 2 were prospective. In total, the studies included 82,852 patients. Laparoscopic appendectomy was associated with a lower mortality rate, a smaller number of postoperative complications and a shorter length of hospital stay, which led to it being recommended by most authors. Four of the ten papers demonstrated that the patients who were qualified for laparoscopic surgery had less comorbidity and were in a lower ASA (American Society of Anaesthesiology) category. Antibiotic therapy as an independent method was assessed in one study in a group of elderly people, on a selected group of 26 patients, and its effectiveness was shown to be 70%. Most studies, however, are highly heterogeneous which significantly hindered comparisons.
Currently, laparoscopic appendectomy seems to be the treatment of choice in the elderly with acute appendicitis. Antibiotic therapy, as an independent method of treatment of acute appendicitis, cannot currently be recommended. However, further, prospective, and better-designed studies are needed, involving a larger number of patients, and primarily dedicated to the elderly.
与人口老龄化相关的人口结构变化意味着外科医生越来越多地接触到老年患者并做出治疗决策。本研究的目的是回顾关于60岁以上患者急性阑尾炎治疗的文献。
使用PubMed数据库对2000年至2015年发表的文献进行了回顾。英文查询“阑尾炎(医学主题词)和老年人(医学主题词)”对应的初始结果数量为260条。基于标题、摘要并最终根据全文进行筛选,最终得到11篇关于60岁以上患者阑尾炎治疗的论文。
9篇论文为回顾性研究,2篇为前瞻性研究。这些研究总共纳入了82852名患者。腹腔镜阑尾切除术与较低的死亡率、较少的术后并发症和较短的住院时间相关,这使得大多数作者推荐该手术。十篇论文中有四篇表明,适合腹腔镜手术的患者合并症较少且美国麻醉医师协会(ASA)分级较低。在一项针对一组26名老年人的研究中,对作为独立治疗方法的抗生素疗法进行了评估,其有效性为70%。然而,大多数研究具有高度异质性,这极大地阻碍了比较。
目前,腹腔镜阑尾切除术似乎是老年急性阑尾炎患者的首选治疗方法。目前,不能推荐将抗生素疗法作为急性阑尾炎的独立治疗方法。然而,需要进一步开展涉及更多患者且主要针对老年人的前瞻性、设计更好的研究。