非颤抖性产热以及甲状腺在金刺毛鼠（Acomys russatus）冷敏感和冷耐受群体中的作用。

Non shivering thermogenesis and implication of the thyroid in cold labile and cold resistant populations of the golden spiny mouse (Acomys russatus).

作者信息

Borut A, Haim A, Castel M

出版信息

Experientia Suppl. 1978;32:219-27. doi: 10.1007/978-3-0348-5559-4_26.

Abstract

The golden spiny mouse is dependent on non shivering thermogenesis (N.S.T.) for thermoregulation at cool ambient temperatures. Mice from the shores of the Dead Sea (Ein-Gedi, EG-mice) lose body heat when exposed to 6 degrees C. Their rate of cooling is linearly correlated to the magnitude of N.S.T. This is true for mice acclimated to 28 degrees C, born in the laboratory or freshly captured. Mice from the high mountains of South Sinai (S-mice) resist cooling under the same conditions and their N.S.T. is about twice that of EG-mice. EG-mice did not acclimate to cold. However thyroxine injections made them cold resistant and their N.S.T. rose to values close to that of S-mice. Light and electronmicroscopy of the thyroids in mice acclimated to 28 degrees C and exposed to 6 degrees C, or injected with TRH suggested intense activity in S-mice and little activity in EG-mice.

摘要

金刺毛鼠在凉爽的环境温度下依赖非颤抖性产热（N.S.T.）来调节体温。来自死海沿岸（Ein-Gedi，EG鼠）的小鼠在暴露于6摄氏度时会散失体热。它们的降温速率与N.S.T.的大小呈线性相关。这对于适应28摄氏度、出生在实验室或刚捕获的小鼠都是如此。来自南西奈高山的小鼠（S鼠）在相同条件下能抵抗降温，其N.S.T.约为EG鼠的两倍。EG鼠不能适应寒冷。然而，注射甲状腺素使它们具有抗寒能力，其N.S.T.上升到接近S鼠的值。对适应28摄氏度并暴露于6摄氏度或注射促甲状腺激素释放激素（TRH）的小鼠甲状腺进行光镜和电镜观察表明，S鼠甲状腺活动强烈，而EG鼠甲状腺活动较弱。